since its original conception in 1959, by nobel physicist richard p feynman, the notion of nanotechnology and its potential ramifications have not only created fascination,but also intense scientific efforts and scrutiny. one of the most promising applications of nanotechnology is in the context of medicine. due to their unique size-dependent properties nanomaterials such as nanoparticles offer...

The utilization of self-microemulsifying premicroemulsion systems (SMEPMS) as templates for preparing poorly water-soluble compounds in the nanosized range represents a promising strategy. Fenofibrate was formulated with n-butyl L-lactate, Tween 80, and a number of cosurfactants (ethanol, 1-propanol, and PEG 600), diluted with the water phase (either water or saccharide solution) and then subje...

A deeper understanding of how the physical properties of particles regulate specific biological responses is becoming a crucial requirement for their successful biomedical application. To provide insights on their design and application, J774A.1 cells are exposed to particles with different diameters (430 nm, 1.9 μm and 4.8 μm), and the size effects on a series of cellular responses in macropha...

The main objective of this work was to prepare nanosized titania (TiO2) particles by mixed reverse microemulsion route. In this work titania was prepared by quaternary microemulsion system (water/surfactant/co-surfactant/ oil-phase). Span-80, Aerosol-OT, n-Propanol, Isooctane, and Titanium tetra isopropoxide (TTIP) were used as surfactant, co-surfactant, oil-phase and titania precursor respecti...

The synthesis of the ZSM-5 and beta zeolites in their nanosized form has been achieved by using simple alkyl-substituted mono-cationic cyclic ammonium cations as OSDA molecules. The particular combination of a cyclic fragment and a short linear alkyl-chain group (preferentially C4) within the monocationic OSDA molecules allows directing the crystallization of nanosized zeolites with excellent s...

nanosized al2o3 powder is synthesized by thermal metal organic chemical vapor deposition (mocvd)combined withplasma. the effects of reaction temperature, pressure, al(ch3)3 (tma) concentration and reactant gases (co2 and o2) on the characteristics of the synthesized al2o3 powders are investigated. the experimental results demonstrate that very fineal2o3 powders with mean particle size of about ...

Top-down approach has been viewed as an efficient and straightforward method to prepare nanosized zeolites. Yet, the mechanical breaking of zeolite causes amorphization, which usually requires a post-milling recrystallization to obtain fully crystalline nanoparticles. Herein we present a facile methodology to prepare zeolite nanocrystals, where milling and recrystallization can be performed in ...

PURPOSE The purpose of this study was to develop a novel and continuous method for preparing a nanosized particle of drug crystals and to characterize its properties. MATERIALS AND METHODS A new apparatus was introduced to crystallize nanosized drug crystals of amitriptyline hydrochloride as a model drug. The samples were prepared in the pure state by ultrasonic spray, and elaborated depositi...

In this paper, we present the development of a method to accurately measure the positive and negative charge distribution of nanosized aerosols using a tandem differential mobility analyzer (TDMA) system. From the series of TDMA measurements, the charge fraction of nanosized aerosol particles was obtained as a function of equivalent mobility particle diameter ranging from 50 to 200 nm. The capa...

In densely populated areas, traffic is a significant source of atmospheric aerosol particles. Owing to their small size and complicated chemical and physical characteristics, atmospheric particles resulting from traffic emissions pose a significant risk to human health and also contribute to anthropogenic forcing of climate. Previous research has established that vehicles directly emit primary ...