Introduction:  This study sought to assess the cytotoxic effects of nanoparticulate and microparticulate calcium sodium phosphosilicate mouthwashes on human gingival fibroblasts (HGFs). Methods: This in vitro study was conducted on HGFs isolated and cultured in a 48-well plate containing standard culture medium for evaluation of four concentrations of the two m...

Aim To compare new remineralizing agents calcium sodium phosphosilicate paste and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste with that of fluoridated toothpaste in remineralization of early carious lesions using scanning electron microscopy and energy-dispersive X-ray (SEM-EDX) analysis. Materials and methods Sixty sound extracted premolars were collected and placed in ...

Objective(s): The present study aimed to assess the in-vitro efficacy of nanoparticulate calcium sodium phosphosilicate mouthwash in the obstruction of dentinal tubules.Materials and Methods: This in-vitro, study was conducted on 120 sections obtained from extracted human premolars, which were etched with citric acid for two minutes and rinsed with distilled water. Afterwards, the section...

BACKGROUND This study aimed to evaluate and compare the efficacy of three desensitizing dentifrices on dentinal hypersensitivity (DH) and salivary biochemical characteristics. MATERIALS AND METHODS A randomized, parallel arm, triple-blinded, clinical trial was conducted over a period of 12 weeks, with a total of three visits: baseline, 6 weeks, and 12 weeks. Calcium sodium phosphosilicate, po...

AIM The aim is to assess the effect of desensitizing toothpaste on dentin hypersensitivity. METHODS We searched PubMed, CENTRAL, and Embase on December 20, 2013. RESULTS Out of the 626 articles searched, a total of 31 randomized controlled clinical trials were included. The Standardized mean differences (SMD) for potassium-containing toothpaste (n = 8) was -1.28 (95% Confidence interval (CI...

OBJECTIVE To investigate the effect of calcium sodium phosphosilicate (CSPS) in treating dentin hypersensitivity (DH) and to compare this effect to that of a negative (placebo) control. MATERIALS AND METHODS Several databases, including Medline, EMBASE, Web of Science, The Cochrane Library, and the Chinese Biomedical Literature Database, were searched to identify relevant articles published t...