in this research at the first enalapril drug and its fullerene derivative were optimized. nbo calculations and nmr for the complexes were carried out at the b3lyp/6-31g* quantum chemistry level. different parameters such as energy levels, the amount of chemical shift in different atoms, the amount of homo/lumo, chemical potential (µ ), chemical hardness (η), the coefficients of hybrid bonds (π,...

in this research at the first metoprolol drug and its fullerene derivative were optimized. natural bond orbital (nbo), nuclear indepndent chemical shift (nics) and finally ir calculations, for these compounds were carried out at the b3lyp/6-31g* quantum chemistry level. different parameters such as energy levels, the amount of chemical shift in different atoms, the amount of homo/lumo, chemical...

To date there has not been any report on catan-ionic hybrid lipidic nano-carriers, let alone a report on applying them to deliver insoluble anti-tumor drugs. Catan-ionic hybrid lipidic nano-carriers containing curcumin (CUR-C-HLN) inherit the merits of catan-ionic systems, hybrid lipidic systems and nano-structured carriers (the second-generation substitute of solid lipidic nano-systems). Catan...

Nanotechnology (nano-materials and nano-process) has been developed for both industrial and medical applications. The use of nano-medicine has been used in bio-imaging and bio-sensing, drug delivery, cancer cell diagnostics and therapeutics [1,2]. Nanoparticles (NPs) can cause tumor cell death by photothermal ablation, photodynamic toxicity, mechanical damage, or increase in the localized drug ...

background :wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. we investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (hsv-1) in cell culture.   methods : in-vitro c...

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

Nano materials is a new type of drug carriers with very promising application. In recent years, great progress was achieved in making drugs own the characteristics of targeted and controlled release via nanotechnologies. This paper addressed the capability of nano drugs on targeting to cells, penetrating through epicyte, controlled release and the security issues resulting from its using. We ga...

By self-organization polymers form a large number of superstructures with characteristic dimensions in the range of a few nanometers up to several micrometers. They can be used to produce in a controlled way a wide range of nano-and microstructured materials such as nanoparticles, nanoporous materials and drug carriers. Applications in the fields of materials science, electronics, molecular bio...