Objective: Coriander (Coriandrum sativum), a member of the Apiaceae family plants, is traditionally used as spice and medicinal plant which has anti-aging, anti-inflammatory, anti-anxiety effects for treatment diabetes. The present study aimed to investigate coriander on H2O2-induced neurotoxicity in PC12 cells. Methods: cells were cultured Dulbecco’s modified Eagle’s medium, various treatments...

Promoted by rapid industrialization and urbanization, the structure spatial pattern of farming in China has changed greatly, nongrain (NGF) become more common. However, excessive NGF some areas is not conducive to sustainable agricultural development threatens China’s food security. In this study, we briefly analyze stage characteristics investigate agglomeration its influencing factors from pe...

objective(s) psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. since studies concerning nerve growth factor (ngf) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on ngf protein levels in various brain regions of rat. materials and methods male wistar rats receiv...

Dental pulp stem cells (DPSCs) secrete neurotrophic factors which may play an important therapeutic role in neural development, maintenance and repair. To test this hypothesis, DPSCs-conditioned medium (DPSCs-CM) was collected from 72 hours serum-free DPSCs cultures. The impact of DPSCs-derived on PC12 survival, growth, migration differentiation investigated. were treated with nerve growth fact...

Objective(s) Psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. Since studies concerning nerve growth factor (NGF) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on NGF protein levels in various brain regions of rat. Materials and Methods Male Wistar rats rec...

Disruption of neurite outgrowth is a marker for neurotoxicity. Persistent organic pollutants (POPs) are potential developmental neurotoxicants. We investigated their effect on in PC12 rat pheochromocytoma cells, absence or presence nerve growth factor (NGF), an inducer neuronal differentiation. Cells were exposed 72 h to defined mixture POPs with chemical composition and concentrations based bl...

Background: Overactive bladder (OAB) is a clinical syndrome characterized by combination of symptoms including urgency, frequency, and nocturia, with or without urinary incontinence. has high prevalence especially in those an older age women, diagnosis depending on the patient’s symptoms. This study aims to assess brain-derived neurotrophic factor (BDNF), nerve growt...

Nerve growth factor (NGF) is a neurotrophic factor that is functional in the survival, maintenance and differentiation of nervous system cells. This protein has three subunits, of which the beta subunit has the main activity. Its structure consists of a cysteine knot motif made up of beta strands linked by disulfide bonds. It can be used as a therapeutic agent in the treatment of many diseases....