,«2-Halogeno Complexes, N-Bromosuccinimide, N-Bromophthalimide, IR Spectra, Crystal Structure The ,«2-halogeno complexes PPh4[X(N-bromosuccinimide)2] and PPh4[X(N-bromophthalimide)2] with X = Cl and Br have been prepared by reactions of N-bromosuccinimide and N-bromophthalimide, respectively, with the corresponding tetraphenylphosphonium halides PPh4X in acetonitrile solutions. The compounds fo...

A pore-forming, cytolytic and lethal polypeptide, equinatoxin II, from the sea anemone Actinia equina, was subjected to oxidation with N-bromosuccinimide to study the role of five present tryptophan residues in structure-function relationships. In the folded toxin molecule, 1-2 tryptophan residues were readily susceptible to oxidation with N-bromosuccinimide, whereas modification of a single re...

The electrokinetic behaviour of normal erythrocytes is compared with that of trypsin-, N-bromosuccinimide-, and tosyl-treated erythrocytes. Reduction in the net negative charge with reduction in ionic strength of the suspending medium and also on treatment with N-bromosuccinimide and trypsin is discussed using a porous non-rigid polyanion as a model for the periphery of the cell membrane. It is...

N-Bromosuccinimide, Zl5-Steroids, Diosgenin, Cholesterol, Stigmastane, Dehydroisoandrosterone The reaction of N-bromosuccinimide with Zl5-steroids such as, diosgenin, cholesterol, stigmasterol and dehydroisoandrosterone were studied. It was found that NBS in a solvent mixture of acetone, water and acetic acid (8:1:0.1) oxidises the olefinic bond of all the previous steroidal compounds to the co...

Three simple spectrophotometric methods have been described for the assay of olanzapine in its pure and pharmaceutical formulations. The direct method (A) is based on the drug oxidation with excess of N-bromosuccinimide in acidic medium and the two indirect methods (B and C) are based on the oxidation of the drug with excess of N-bromosuccinimide and cerium(IV)sulfate, followed by the reaction ...

two sensitive spectrophotometric methods are presented for the assay of pantoprazole sodium sesqui hydrate (pnt) in bulk drug and in formulations using n-bromosuccinimide (nbs) and two dyes, methyl orange and indigo carmine, as reagents. the methods involve the addition of a known excess of nbs to pnt  in acid medium, followed by determination of unreacted oxidant by reacting with a fixed amoun...