the purpose of this study was to evaluate the effects of different time combinations of dexamethasoneand acetylcysteine on experimentally induced corneal ulcers in dogs. experimental corneal wounds werecreated surgically to the anterior one third of the cornea in the center of all eyes of 15 mixed breed dogs. the eyes were divided into five groups according to planned post-operative medications...

introduction it has long been known that ionizing radiation can lead to detrimental effects in normal cells. in this light, radioprotective chemicals have been used to decrease morbidity or mortality caused by ionizing irradiation. this study aimed to evaluate the radio-protective effect of n-acetylcysteineagainst radiation-induced mortality in male mice. materials and methods 52 healthy male m...

conclusions in conclusion, we suggest that tq may be used as a prophylactic agent against nephrotoxicity, especially in instances of tubular injury. however, human-based studies are still needed. objectives in this study, we investigated the comparative nephroprotective effects of silymarin, n-acetylcysteine (nac), and thymoquinone (tq) in animal models (rats) in which we induced nephrotoxicity...

airway mucus hypersecretion and increased oxidative stress are clinical and pathophysiological features of asthma exacerbation. we studied effects of n-acetylcysteine (nac) as a mucolytic and antioxidant agent in asthma exacerbation. in this randomized, single-blinded, placebo-controlled study 50 patients ( 17 male, 33 female, mean age 48.94±13.68) with asthma exacerbation were randomized to re...

background acoustic trauma is an injury to the hearing mechanisms in the inner ear due to excessive noise. this injury is the most prevalent cause of sensorineural hearing loss in humans, especially from occupational exposure. previous studies have shown the essential role of free radical formation in the inner ear hearing loss caused by acoustic trauma. objectives this study was performed to d...

Introduction: Anthracyclines are one of the classes of chemotherapy drugs that  are widely used to treat many types of cancers including breast cancer. Taking this class of medications has a significant relationship with cardiac dysfunction. N-acetylcysteine has antioxidant properties and may be effective in preventing cardiac dysfunctions. In this study, we investigated the effect of N-acetylc...

N-acetylcysteine-derived carbon dots In article 2300533 by Jianwei Du, Hao Chen, Huihui Wang, and co-workers, a novel nanozyme derived from N-acetylcysteine is designed developed for free radical scavenging in intervertebral disc degeneration, which shows higher multienzyme activities antioxidant capacity.