Journal:
:iranian journal of basic medical sciences
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farzin hadizadeh department of medicinal chemistry, school of pharmacy and biotechnology research center, mashhad university of medical sciences, mashhad, iran
mohammad fatehi atlantic centre for comparative biomedical research, charlottetown, pei, canada.
(former faculty member of department of physiology and pharmacology, faculty of medicine, mashhad university
of medical sciences, mashhad, iran)
zahra fatehi-hassanabad atlantic centre for comparative biomedical research, charlottetown, pei, canada.
(former faculty member of department of physiology and pharmacology, faculty of medicine, mashhad university
of medical sciences, mashhad, iran)
mojgan zandieh department of medicinal chemistry, school of pharmacy and biotechnology research center, mashhad university of medical sciences, mashhad, iran
objectives in order to provide a pharmacological profile for some newly synthesized dihydropyridines, we investigated their effects on the isolated rat colon segments and the isolated rat atrium contractility. the tested compounds include alkyl ester analogues of nifedipine, in which the ortho-nitrophenyl group at position 4 is replaced by 2-alkylthio-1-benzyl-5-imidazolyl substituent, and nife...