zearalenone (zea) mycotoxin is a potent estrogenic metabolite. it is the primary toxin causing infertility, abortion or other breeding problems. a hplc method was validated for zea in foods using a monolithic column with sample clean-up on an immunoaffinity column. a certified reference material (crm) from fapas (uk) was analyzed. a survey of zea was performed on the 72 samples of rice, bread, ...

It is recognized that mycotoxins can cause a variety of adverse health effects in animals, including altered gastrointestinal barrier function. It is the aim of the present study to determine whether mycotoxin-contaminated diets can alter the oral bioavailability of the antibiotics doxycycline and paromomycin in pigs, and whether a mycotoxin adsorbing agent included into diets interacts with th...

the contamination of cereals with toxic secondary metabolites of fungi, mycotoxins, is a permanent challenge in human health. these toxins are produced by a few fungi are mainly of the genera fusarium , aspergillus and penicillium . ochratoxin a is a nephrotoxic mycotoxin, which possesses carcinogenic, teratogenic, immunotoxic and possibly neurotoxic properties. zearalenone is a non-steroidal e...

Mycotoxin contamination of food and feedstuffs is among the top priorities for human and animal safety. The currently used techniques for mycotoxin determination, either chromatography or ELISA, are unsuitable for routine in-field assessment. There is an urgent need for other accurate, simple and cost-effective techniques that can be used as a screening tool for a rapid estimation of mycotoxin ...

Mycotoxin contamination threatens health and life of humans and animals throughout the food supply chains. Many of the mycotoxins have been proven to be carcinogens, teratogens and mutagens. The reliable and sensitive sensing methods are requested to monitor mycotoxin contamination. Advanced sensors based on antibodies or aptamers boast the advantages of high sensitivity and rapidity, and have ...

AIM This study was conducted to examine the potential of mycotoxin binder in ceasing zearalenone (ZEN) effect on mice reproduction. ZEN mycotoxin can induce reactive oxygen species that may cause damage and cell death. ZEN is estrogenic so that it may affect the reproductive organs failure. MATERIALS AND METHODS Mycotoxin binder administration to female mice exposed to ZEN was aimed to count ...

This article brings an overview of mycotoxin co-occurrence in foods in Croatia and neighbouring countries and experimental data from mycotoxin interaction studies involving Fusarium toxins, ochratoxin A (OTA), and aflatoxin B(1) (AFB(1)). Only a few studies of combined mycotoxin toxicity have employed a mathematical/ statistical design, while others have used common statistics in order to compa...

Possible health risks associated with occupational inhalation of mycotoxin-containing dust remain largely unknown, partly because methods for mycotoxin detection are not sensitive enough for the small dust masses obtained by personal sampling, which is needed for inhalable exposure measurements. Specific and sensitive PCR detection of fungi with mycotoxin-producing potential seem to be a good s...

This study aimed to assess the occurrence of toxigenic fungi and mycotoxin contamination in stored wheat grains by using advanced molecular and analytical techniques. A multiplex polymerase chain reaction (PCR) strategy was established for rapid identification of mycotoxigenic fungi, and an improved analytical method was developed for simultaneous multi-mycotoxin determination in wheat grains b...