Macrophages undergo apoptosis after infected by Mycobacterium tuber- culosis (M.tb), which is regulated by tumor necrosis factor alpha (TNF-alpha) and has a direct correlation with killing of intracellular bacilli. In order to clarify the role of isoniazid (INH) in the modulation of macrophages apoptosis and intracellular bacilli replication, we performed the following studies using an INH-resi...

background : medicinal use of plants dates long back in the history of the human beings and has recently gained a great deal of importance in treating different diseases. due to the importance of pseudomonas aeroginosa strains as agents responsible for common secondary infections and their resistance to antibiotics and disinfectants, the present study aimed at investigating the antimicrobial ef...

From embryological consideration; (Keith* 1948; Hasvey & Burr, 1926; Johnstone, 1946) the two layers of meninges i.e. pia a nd arachnoidmater as well as the brain are developed from the ectodermal tissue, whereas, the duramater is developed from mesderm. It is not distinctly clear, why the mycobacterium tuber* culosis has affinity for the tissue derived from ectoderm and not for those derived f...

The objective of this study was to determine the prevalence and factors associated with multidrug-resistant tuberculosis (MDR-TB) at Siriraj Hospital, Bangkok, Thailand. We conducted a retrospective unmatched case-control study of patients clinically diagnosed and microbiologically confirmed to have tuber- culosis (TB) at Siriraj Hospital from 2010 to 2012. Patient characteristics, clinical dat...

Previous work on human subjects (9) has shown that the polysaccharide associated with serum proteins is significantly elevated in malig nancy. Little is known concerning the correlation between this elevation and the cancerous condi tion. Work in this laboratory has shown that the serum polysaccharide of dogs is increased in sev eral types of experimental inflammation (7). An elevation also occ...

Civanar amirtam is a siddha herbo- mineral formulation prescribed for rheumatism, bronchial asthma, tuber culosis and leprosy. Of the nine ingredients which constitute the preparation, four are inorganic and the others are plant drugs, Attempts have been made to chemically analyse and to identify the presence of each ingredient in the medicine to lay down standards. The identification of variou...

conclusions although very rare, mdr miliary tb can be seen in immunocompetent subjects. we, thereby, emphasize that early recognition and initiation of treatment are associated with a significant improvement in outcomes. tuberculosis remains a serious worldwide health problem associated with high morbidity and mortality. case presentation our case was a young female patient with in vitro fertil...