two  simple  protocols  for  the  synthesis  of  1,  2,  4,  5-  tetrasubstitutedimidazoles  using  nano-spa  as  a  reusable,  eco-  friendly,  inexpensive,  and  efficient  catalyst  are  reported.  short   reaction  times,  high  yields,  scale-up  and  easy  workup  are  the   advantages of these protocols.

the efficient and environmentally friendly method for the one-pot synthesis of polyhydroquinolines has been developed in the presence of cuo nanoparticles. the multi-component reactions of aldehydes, dimedone, ethyl acetoacetate andammonium acetate were carried out under solvent-free conditions to afford some polyhydroquinoline derivatives. this method provides several advantages including high...

a very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under 80 °c using sucrose as natural and biodegradable catalyst in water. this method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. therefore, this methodology is entirely green ...

cui nanoparticles as an expedient and recyclable catalyst for the synthesis of n-cyclohexyl-3-aryl-quinoxaline-2-amines in ethanol via a multi-component reaction are established. the products were separated from the catalyst simply by filtration. the catalyst could be recycled and reused for several times without noticeably decreasing the catalytic activity.

a simple and mild one-pot three-component reaction for the preparation 1,4-dihydropyridines has been developed from various aldehyde substrates, 1,3-dicarbonyl compounds (dimedone) and ammonium acetate (hantzsch method) in the presence of a catalytic amount of phospho sulfonic acid (psa) as an efficient and heterogeneous solid acid in etoh at room temperature. preparation of psa is straightforw...

Three-component reactions have emerged as useful methods because the combinationof three components to generate new products in a single step is extremely economical,among the multi-component reactions. A green, simple, efficient, and cost-effective procedure has been carried out by the synthesis of dihydropyrimidinonesin Biginelli’s condensation of ethyl cyanoacetate, aldehyde and urea or thio...

In this work, the efficiency, generality and applicability of new Bronsted acidic ionic liquid (BAIL) 1-methyl-3-(2-(sulfooxy)ethyl)-1H-imidazol-3-ium chloride {[Msei]Cl} as heterogeneous and green catalyst for organic transformations are studied. Herein, the following one-pot multi-component reactions in the presence of [Msei]Cl are investigated: (i) the synthesis of quinoxaline derivatives fr...

in this work, the efficiency, generality and applicability of new bronsted acidic ionic liquid (bail) 1-methyl-3-(2-(sulfooxy)ethyl)-1h-imidazol-3-ium chloride {[msei]cl} as heterogeneous and green catalyst for organic transformations are studied. herein, the following one-pot multi-component reactions in the presence of [msei]cl are investigated: (i) the synthesis of quinoxaline derivatives fr...