BACKGROUND Müllerian inhibiting substance, produced constitutively by the prepubertal testes, promotes involution of the müllerian ducts during normal male sexual differentiation. In children with virilization and nonpalpable gonads, only those with testicular tissue should have detectable serum concentrations of müllerian inhibiting substance. METHODS We measured serum mullerian inhibiting s...

Study sample No sample size appears to have been determined in the planning phase of the study. In addition, no retrospective power calculations were reported. The authors reported that a group of MIS-TKA patients was compared with a group of 50 traditional TKA patients, but it was unclear how many patients were in the MIS-TKA group. The authors then reported that all patients (n=159) were coho...

Ten laboratories in an external quality assurance scheme used the same assay to measure anti-müllerian hormone concentration (Beckman Coulter Gen II) and received twenty serum samples distributed over a 15 month period. The mean bias for all results was only -0.089%, but there was large coefficient of repeatability of 38.8% (sample bias ranged from -37.9% to +54.7%). While each laboratory showe...

OBJECTIVE To determine age-specific serum anti-Müllerian hormone (AMH) values for women presenting to U.S. fertility clinics. DESIGN Retrospective study. SETTING Single clinical reference laboratory. PATIENT(S) A total of 17,120 women of reproductive age ranging from 24 to 50 years old. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Determination of single-year median and mean AMH valu...

This review is a tutorial for scientists interested in the problem of protein structure prediction, particularly those interested in using coarse-grained molecular dynamics models that are optimized using lessons learned from the energy landscape theory of protein folding. We also present a review of the results of the AMH/AMC/AMW/AWSEM family of coarse-grained molecular dynamics protein foldin...

When some magnetic field lines connect a Kerr black hole with a disk rotating around it, energy and angular momentum are transferred between them. If the black hole rotates faster than the disk, ca&solm0;GMH>0.36 for a thin Keplerian disk, then energy and angular momentum are extracted from the black hole and transferred to the disk (MH is the mass and aMH is the angular momentum of the black h...

An eighteen month old phenotypically and genotypically normal male child was admitted with a left inguinal hernia and a right undescended testis. At operation, he was found to have a uterus, bilateral fallopian tubes, and a vagina in the left hernial sac. Bilateral orchidopexies and excision of the persistent Mullerian duct structures were carried out. This rare case of persistent Mullerian duc...