Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid, which is widely used in food industry. Glutamate plays an important role in principal brain functions including formation and stabilization of synapses, memory, cognition, learning, as well as cellular metabolism. However, ingestion of foodstuffs rich in monosodium glutamate can result in the outbreak of severa...

Objective: Female metabolism is highly responding towards diet associated changes. Monosodium glutamate is a popular flavor enhancer, which is widely used to develop umami taste. Young female generation nowadays deals with more issues related to metabolism and fertility. Present study is an effort to monitor the effect of monosodium glutamate oral consumption on female mice health and obesity. ...

conclusions in the literature, it was observed that short-term msg exposure does not cause significant histological changes in the kidneys, liver, or brain cortex. these findings should be re-evaluated in additional long-term studies. background monosodium glutamate (msg) is a widely-used flavor enhancer and stabilizer in ready-made or packaged foods. the excessive use of msg has been shown to ...

BACKGROUND: Monosodium glutamate is commonly used in our foods and reported many physiological effects. Propolis is a natural product widely used in folk medicine due to its bioactive compounds. It is considered one of the richest sources of phenolic acids and flavonoids. METHODS: The phenolic acids and flavonoids content of Saudi Arabian propolis was determined by HPLC analysis. Three groups o...

OBJECTIVES The aim of this study was to evaluate cardiovascular autonomic function in a rodent obesity model induced by monosodium glutamate injections during the first seven days of life. METHOD The animals were assigned to control (control, n = 10) and monosodium glutamate (monosodium glutamate, n = 13) groups. Thirty-three weeks after birth, arterial and venous catheters were implanted for...

The effect of coenzyme Q10 on oxidative stress parameters and testicular tissue damage in rats following monosodium glutamate induced excitatory intoxication

BACKGROUND Monosodium glutamate (MSG) is a commonly used food additive and there is growing concern that excitotoxins such as MSG play a critical role in the development of several hepatic disorders. OBJECTIVES The histochemical effect of monosodium glutamate was investigated on the liver of adult Wistar rats. METHODS Adult male Wistar rats (n = 24), with an average weight of 230 g were ran...

Feeding behavior is regulated by feeding-related peptides in the hypothalamus. The neurons of the arcuate nucleus (ARC), which produces feeding-related peptides, develop and function by three weeks of age in rodents. Because rodents are weaned at three weeks, we studied whether the process of weaning is involved in the development of ARC neurons using monosodium glutamate. Rat pups injected neo...

We examined the methodological approach to the assessment of monosodium glutamate intake. The high carbohydrate and low fat consumption characteristic of this study population would be conducive to the development of metabolic syndrome. However, anomalies in the assessment of dietary information limits conclusion to a causal link of monosodium glutamate to metabolic syndrome and overweight beca...