introduction:it is well-recognized that collimator-detector response (cdr) is the main image blurring factor in spect.  in this research, we compensated the images for cdr in molecular spect by using stir reconstruction framework. methods: to assess resolution recovery capability of the stir, a phantom containing five point sources along with a micro derenzo phantom were investigated. influence...

myocardial ischemia (mi) resulting in infarction is an important cause of mortality and morbidity worldwide. acute ischaemia rapidly impairs myocardial contractile function. myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. hibernation is now thought to be the consequence o...

Introduction:It is well-recognized that collimator-detector response (CDR) is the main image blurring factor in SPECT.  In this research, we compensated the images for CDR in molecular SPECT by using STIR reconstruction framework. Methods: To assess resolution recovery capability of the STIR, a phantom containing five point sources along with a micro Derenzo p...

Molecular imaging with ictal single photon emission computed tomography (SPECT) is an established functional imaging modality for the presurgical evaluation of patients with refractory partial onset seizures. SPECT coregistered on to the MRI has greater sensitivity to identify the ictal onset zone. Ictal SPECT should always be interpreted in the context of other presurgical investigations. Icta...

Dual isotope single photon emission computed tomography (SPECT) and dual tracer positron emission tomography (PET) imaging have great potential in clinical and molecular applications in the pediatric as well as the adult populations in many areas of brain, cardiac, and oncologic imaging as it allows the exploration of different physiological and molecular functions (e.g., perfusion, neurotransm...

Molecular imaging has witnessed a tremendous change over the last decade. Growing interest and emphasis are placed on this specialized technology represented by developing new scanners, pharmaceutical drugs, diagnostic agents, new therapeutic regimens, and ultimately, significant improvement of patient health care. Single photon emission computed tomography (SPECT) and positron emission tomogra...

Molecular Imaging Techniques Molecular imaging of the brain aims to quantify various biological processes via the modeling of interactions between a molecular probe and a molecule of interest naturally occurring in a living organism. Brain molecular-imaging techniques such as positron emission tomography (PET) and single photon emission tomography (SPECT) allow clinical investigators to record ...