Catharanthus roseus (L.) G.Don is a plant which produces anticancer and anti-mitotic indole alkaloids. Colchicine is an anti-mitotic drug. Anti-mitotic effects of Vinca herbacea Waldst. & Kit. indole alkaloids is unknown. The study were evaluated the antimitotic effect of alkaloids of V. herbacea, Catharanthus roseus andcolchicineon mitosis and microtubule arrangement of human blood cells. In t...

genus onobrychis is an important forage crop consisting of approximately 130 annual and perennial species. the present research focused on the cytological studies of embryogenic (e) and non-embryogenic (ne) callus as well as root meristem cells of in vitro and in vivo grown plants. on the contrary to the previous studies, a diploid viciifolia variety with 2n= 2x= 16 chromosomes was observed for...

the aim of this study was the evaluation of acute genotoxic effect of effluent water of thermo-power plant by means of tradescantia root tips micronucleus test (mn), mitotic index and cell aberrations.   tradescantia , was experimentally treated (for 24 h), with effluent water of thermo-power plant in different dilution ratios (negative control – distilled water; primary untreated effluent wate...

meningiomas are slow-growing neoplasms which recur locally, their morphologic grading is simple but do not always correlate with patient outcome. the aim of present study is to evaluate the status of progesterone receptor (pr) and proliferation marker ki67 in various grades of meningioma in a group of iranian patients. 78 cases of meningioma were selected from the file of a hospital university....

Background: Most of the cytogenetic dosimetry, except Premature Chromosome Condensation assay, saturates at 6 Gy. Present studies are aimed to assess feasibility of simple CB-MN assay for prescreening of high dose accidental exposures. Materials and Methods: Human peripheral blood lymphocytes from two donors were gamma irradiated to different doses ranging from 0-15Gy, cultured for 72 h. Cytoch...

phytohemagglutinin (pha) is a lectin, obtained from the red kidney bean that binds to the membranes of t-cells and stimulates metabolic activity, cell division, etc. the object of this research was the comparison between self made pha (indigenous) and imported commercial one, following conventional and high resolution cell synchronization technique (hrcs) .from each blood sample of healthy indi...

ABSTRACT First Person is a series of interviews with the first authors selection papers published in Journal Cell Science, helping early-career researchers promote themselves alongside their papers. Joanna Wenda author on ‘ Mitotic chromosome condensation requires phosphorylation centromeric protein KNL-2 C. elegans’, JCS. PhD student (in process graduating) lab Florian Steiner at Department Mo...

background: from the time immemorial man has been exposed to ionizing radiation from the environment in which he lives. radiation protection concepts and philosophy have been evolving over the past several decades. materials and methods: the radioprotective of effect of aloe vera leaf extract (1000 mg /kg b.wt. orally for 15 consecutive days) has been studied against 6 gy of gamma radiation in ...

background: for xenograft models of triple-negative breast cancer (tnbc) to be valuable in development of molecularly-targeted drugs, careful characterization is essential to their validation. the present study aimed to validate the tnbc xenograft model with a specific focus on angiogenesis. methods : twelve tnbc xenograft tumors and 12 human breast cancer tumors (htnbc) were included in this s...