introduction cow’s milk allergy is the most common food allergy in children. symptoms usually involve the skin and the gastrointestinal and respiratory tracts. gastrointestinal tract manifestations of cow’s milk allergy are nonspecific, and are the only type that can be diagnosed in all age groups. here, we report a rare case of cow's milk allergy in an infant with hypoalbuminemia and malnutrit...

BACKGROUND Cow's milk allergy is the most common childhood food allergy. Previously we noted that children who outgrew their milk allergy had milk-specific IgE antibodies primarily directed against conformational epitopes; those with persistent milk allergy also had IgE antibodies directed against specific sequential epitopes. OBJECTIVE Because high temperature largely destroys conformational...

BACKGROUND Cow's milk allergy is the most prevalent food hypersensitivity, affecting 2-3% of infants, but it tends to resolve with age. Cow's milk-specific immunoglobulin E in the serum is an important measure in the diagnosis and follow-up of infants and children with cow's milk allergy. OBJECTIVES To examine the relation between CmsIgE and the probability of resolution of milk allergy. ME...

cow’s  milk  anaphylaxis is  the  most  common  food-induced  anaphylaxis in  iranian children. the clinical and laboratory findings of cow’s milk anaphylaxis are evaluated in this study. all children who had experienced cow’s  milk anaphylaxis and had been referred to immunology, asthma and allergy research center during a 5-year period were considered. after fulfilling a questionnaire, patien...

Our knowledge about the time trend of cow’s milk allergy prevalence is very limited, however there some indirect data favoring the increase of the cow’s milk allergy prevalence. There are several studies reporting that food allergy is increased among children of all ages, both gender and different races/ethnicities. Several national health surveys in USA recently indicated that food allergy pre...

PURPOSE The rate of cow's milk allergy diminishes with age. There is not enough information concerning geographical trends in persistent cow's milk allergy in children. The objective of the study was to evaluate the prevalence of persistent cow's milk allergy in children previously diagnosed with IgE-mediated cow's milk allergy (CMA). MATERIAL/METHODS Diagnosis of cow's milk allergy was estab...

BACKGROUND Cow's milk allergy is the most common food allergy in children, with rates estimated at 1.9% to 4.9%. Clinical phenotypes of cow's milk allergy are varied and involve 1 or more target organs, with the main targets being the skin, respiratory system, and gastrointestinal tract. To date, no studies have investigated detailed cardiac function in children with cow's milk allergy. The cur...

OBJECTIVE There are few studies on the natural history of milk allergy. Most are single-site and not longitudinal, and these have not identified a means for early prediction of outcomes. METHODS Children aged 3 to 15 months were enrolled in an observational study with either (1) a convincing history of egg allergy, milk allergy, or both with a positive skin prick test (SPT) response to the tr...

BACKGROUND There have been several reports on neonates with milk allergy in a neonatal ward. This type of allergy is mostly categorized as a non-IgE-mediated food allergy. Although most cases of milk allergy occur in the first few months of life, the differences in clinical characteristics between premature and full-term neonates are still unclear. OBJECTIVE This study aimed to clarify the di...

Background Milk allergy is the most common food allergy in infants and young children. Typical milk allergy symptoms involve hives, vomiting, or even anaphylaxis. For cow’s milk, strict avoidance is difficult because milk proteins are very ubiquitous. Oral immunotherapy (OIT) is an effective therapeutic option to induce milk oral tolerance. However, the immune mechanisms underlying this treatme...