1/M Acne conglobata 8 to 0 0.25 60.5 8.1 None None Elevated serum cholesterol, creatinine kinase at last visit, mild cheilitis 2/M Acne fulminans 8 to 2 0.18 55.5 10.0 Oral methylpred nisolone Adapalene gel Transient elevation of serum TG, mild cheilitis 3/F Acne fulminans 8 to 4 0.15 34.8 7.4 Oral prednisolone Clindamycin/ benzoyl-peroxide Transient elevation of serum cholesterol, γ-GT, TG, mi...

CLINICAL QUESTION What are the most effective treatment(s) for mild, moderate, severe, and hormonally driven acne? RESULTS Mild acne responds favorably to topical treatments such as benzoyl peroxide, salicylic acid, and a low-dose retinoid. Moderate acne responds well to combination therapy comprising-topical benzoyl peroxide, antibiotics, and/or retinoids, as well as oral antibiotics in refr...

BACKGROUND Acne vulgaris is a common skin condition, which affects most adolescents at some point in their lives. It has been found to have a significant impact on their psychological well-being and has been associated with depression and suicide ideation. Many studies have assessed the impact of acne vulgaris on the quality of life (QoL) in different population subgroups around the world, but ...

one of the common chronic inflammatory skin diseases is acne vulgaris that affects up to 80% of a teen-age population. the progress of acne lesions is due to colonization of propionibacterium acnes (p .acnes) in hair follicles. treatment of acne includes topical or systemic therapy or combination therapy, with a tendency to perform topical therapy in mild to moderate acne. nanoemulsions, small ...

Background: Comedone formation has an essential role in pathophysiology of acne, therefore destroying of comedones and preventing of comedone formation is very important in acne treatment. Objective: To determine the effect of superficial peeling with 70% glycolic acid in the improvement of acne. Patients and Methods: In this open clinical trial without control group, 30 patients with acn...

acne is the most common skin disease and isotretinoin is the most powerful drug among the various drugs used for its treatment, but it has some adverse effects. the aim of this study was to evaluate the effect of isotretinoin on depression and quality of life of a group of patients undergoing isotretinoin therapy before and after the treatment course.in this prospective study, 98 patients with ...

Objective: This study was to verify if the skin cleanser could help decrease the infection ratio of Demodex Folliculorum in acne patients. Methods: 132 participants with mild to moderate vulgaris acne participated in this monocentric, prospective, double-blind study. Dermatologists grading and Standardized Skin Surface Biopsy were performed in baseline and after using cleanser only 7 d later. R...

BACKGROUND With the increase in antibiotic-resistant strains of microorganisms in acne lesions, the search for alternative treatment methods has become important. We studied the efficacy of a combination of the antiseptic substances octenidine dihydrochloride and 2-phenoxyethanol (O/P) in mild to moderate inflammatory acne vulgaris. METHODS Thirty patients were instructed to apply O/P once or...

BACKGROUND Finding an effective treatment for acne that is well tolerated by the patients is a challenge. One study has suggested the efficacy of tea tree oil in treatment of the acne vulgaris. AIM To determine the efficacy of tea tree oil in mild to moderate acne vulgaris. METHODS This was a randomized double-blind clinical trial performed in 60 patients with mild to moderate acne vulgaris...