نتایج جستجو برای: Middle ear infection

تعداد نتایج: 634657  

Journal: :iranian journal of otorhinolaryngology 0
mohammad ali damghani department of otorhinolaryngology, kerman university of medical sciences, kerman, iran. ali barazin department of otorhinolaryngology, kerman university of medical sciences, kerman, iran.

introduction: chronic otitis media (com), a persistent and durable inflammation and infection of the middle ear, is a common disorder. alterations in the contralateral ear in sufferers have been observed in recent years. because only a few studies have been reported in this area, we performed this study in order to assess alterations in the contralateral ear of patients with com.   materials an...

Journal: :Lijecnicki vjesnik 2015
Martina Maričić Zrinka Bošnjak Srećko Branica

Middle ear infection is one of the most common childhood infections and the leading reason for antibiotic prescriptions. Although the etiological diagnosis is rarely discovered, successful identification of pathogens depends on properly collected sample, chosen method and microbiological analysis made on time. The most common bacterial pathogen is Streptococcus pneumoniae. Others include Haemop...

Journal: :Pathogens and disease 2015
Kyle A Murrah Roberta L Turner Bing Pang Antonia C Perez Jennifer L Reimche Lauren B King John Wren Uma Gandhi W Edward Swords David A Ornelles

Adenoviral infection is a major risk factor for otitis media. We hypothesized that adenovirus promotes bacterial ascension into the middle ear through the disruption of normal function in the Eustachian tubes due to inflammation-induced changes. An intranasal infection model of the chinchilla was used to test the ability of type 5 adenovirus to promote middle ear infection by Streptococcus pneu...

2016
Derek Hood Richard Moxon Tom Purnell Caroline Richter Debbie Williams Ali Azar Michael Crompton Sara Wells Martin Fray Steve D. M. Brown Michael T. Cheeseman

Acute otitis media, inflammation of the middle ear, is the most common bacterial infection in children and, as a consequence, is the most common reason for antimicrobial prescription to this age group. There is currently no effective vaccine for the principal pathogen involved, non-typeable Haemophilus influenzae (NTHi). The most frequently used and widely accepted experimental animal model of ...

Journal: :Infection and immunity 2014
Kirsty R Short Maren von Köckritz-Blickwede Jeroen D Langereis Keng Yih Chew Emma R Job Charles W Armitage Brandon Hatcher Kohtaro Fujihashi Patrick C Reading Peter W Hermans Odilia L Wijburg Dimitri A Diavatopoulos

Otitis media (OM) (a middle ear infection) is a common childhood illness that can leave some children with permanent hearing loss. OM can arise following infection with a variety of different pathogens, including a coinfection with influenza A virus (IAV) and Streptococcus pneumoniae (the pneumococcus). We and others have demonstrated that coinfection with IAV facilitates the replication of pne...

Journal: :Antimicrobial agents and chemotherapy 2000
S I Pelton M Figueira R Albut D Stalker

Therapy for otitis media (OM) due to resistant Streptococcus pneumoniae (MIC of penicillin, >/=2.0 microgram/ml) is challenging. Linezolid, an oxazolidinone, represent a new class of antimicrobial agents with excellent in vitro activity against penicillin-resistant S. pneumoniae; however, in vitro activity against nontypeable Haemophilus influenzae (NTHI) is limited. We evaluated its efficacy a...

Journal: :The Journal of infectious diseases 2011
Kirsty R Short Dimitri A Diavatopoulos Ruth Thornton John Pedersen Richard A Strugnell Andrew K Wise Patrick C Reading Odilia L Wijburg

Otitis media (OM) is one of the most common childhood diseases. OM can arise when a viral infection enables bacteria to disseminate from the nasopharynx to the middle ear. Here, we provide the first infant murine model for disease. Mice coinfected with Streptococcus pneumoniae and influenza virus had high bacterial load in the middle ear, middle ear inflammation, and hearing loss. In contrast, ...

Journal: :Journal of immunology 2012
Sejo Oh Jeong-Im Woo David J Lim Sung K Moon

The inner ear, composed of the cochlea and the vestibule, is a specialized sensory organ for hearing and balance. Although the inner ear has been known as an immune-privileged organ, there is emerging evidence indicating an active immune reaction of the inner ear. Inner ear inflammation can be induced by the entry of proinflammatory molecules derived from middle ear infection. Because middle ea...

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