نتایج جستجو برای: Microgravity Condition

تعداد نتایج: 317796  

Objective(s): Studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. Here we investigated the effects of simulated microgravity on neural differentiation of human adipose-derived stem cells (ADSCs). Materials and Methods:We have used a fast rotating clinostat (clinorotation) to simulate microgravity condition. R...

Introduction: VCAM-1 and Tie1 are endothelial molecule and receptor, respectively that may participate in atherosclerosis disease. Endothelial cells are very sensitive to mechanical forces, including microgravity and the morphological and functional changes in this condition. To examine the effect of gravity on atherosclerosis disease, we analyzed the expression of VCAM-1 and Tie1 genes in micr...

Journal: :iranian journal of basic medical sciences 0
vajiheh zarrinpour department of biology, fars science and research branch, islamic azad university, marvdasht, iran department of biology, marvdasht branch, islamic azad university, marvdasht, iran zahra hajebrahimi aerospace research institute, ministry of science research and technology, tehran, iran mojtaba jafarinia department of biology, fars science and research branch, islamic azad university, marvdasht, iran department of biology, marvdasht branch, islamic azad university, marvdasht, iran

objective(s): studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. here we investigated the effects of simulated microgravity on neural differentiation of human adipose-derived stem cells (adscs). materials and methods:we have used a fast rotating clinostat (clinorotation) to simulate microgravity condition. re...

Background: Mesenchymal stem cells (MSCs) are multipotent cells able to differentiating into a variety of mesenchymal tissues including osteoblasts, adipocytes and several other tissues. Objectives: Differentiation of MSCs into fibroblast cells in vitro is an attractive strategy to achieve fibroblast cell and use them for purposes such as regeneration medicine. The goal of this s...

2016
Shen Zhang Dahan Zheng Yonggen Wu Wei Lin Zaichong Chen Luhe Meng Jun Liu Ying Zhou

BACKGROUND Growing cells in simulated weightlessness condition might be a highly promising new technique to maintain or generate tissue constructs in a scaffold-free manner. There is limited evidence that microgravity condition may affect development of ovarian follicles. The objective of the present study was to investigate the effects of simulated microgravity on the in vitro development of m...

 Background: Hindlimb Unloading (HLU) is used to simulate microgravity in rats and has been shown to decrease contractile response in the abdominal aorta. The aim of present study was to investigate the contractile responses of smooth muscle of thoracic aorta following acute and chronic microgravity treatment.  Methods: Male adult rats (Wistar) were subjected to HLU for 3 and 20 days t...

2011
Balwant Rai Jasdeep Kaur Bernard H. Foing

Objective. HDT bed rest condition is a simulated microgravity condition in which subject lies on bed inclined -6 degree feet up. To determine the influence of a simulated microgravity (HDT bed rest) on oral cavity, 10 healthy male volunteers were studied before, during, just after, and after 6 weeks of the simulated microgravity condition of -6° head-down-tilt (HDT) bed rest. Materials and Meth...

2017
Vajiheh Zarrinpour Zahra Hajebrahimi Mojtaba Jafarinia

OBJECTIVES Studies have confirmed that microgravity, as a mechanical factor, influences both differentiation and function of mesenchymal stem cells. Here we investigated the effects of simulated microgravity on neural differentiation of human adipose-derived stem cells (ADSCs). MATERIALS AND METHODS We have used a fast rotating clinostat (clinorotation) to simulate microgravity condition. Rea...

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