As digital microfluidic biochips become widespread in safety-critical biochemical applications, system dependability emerges as a critical performance parameter. The dynamic reconfigurability inherent in digital microfluidic biochips can be utilized to bypass faulty cells, thereby supporting defect/fault tolerance. In this paper, we propose three different reconfiguration techniques and the cor...

Dependability is an essential attribute for microfluidic biochips that are being developed for safety-critical applications such as point-of-care health assessment, air-quality monitoring, and food-safety testing. Therefore, these devices must be adequately tested after manufacture and during bioassay operations. This paper describes testing and diagnosis techniques for droplet-based "digital" ...

Microfluidic biochips are becoming more and more popular in biomedical laboratory and also industry. Different from the continuous-flow microfluidic systems, a new generation of microfluidic biochips, referred to as digital microfluidic chips, has evolved over time and it offers advantages such as on-line reconfiguration and fault-tolerant operation. The principles behind the digital microfluid...

This work highlights the importance of surface modification on quality and quantity spheroid formation microfluidic-based biochips.

Digital Microfluidic Biochips (DMFBs) have been widely used in Lab-on-a-Chip (LoC) for disease diagnosis and treatment applications. Biological sample to be processed are originally analog continuous flow. To convert it into digital droplets for DMFB processing, a microfluidic droplet dispenser acting as an analog-to-digital converter (ADC) is needed. In this paper, a highthroughput analog-to-d...

1. Abstract In the previous checkpoint, design for biochips (see Figure 1). Figure 1: We are addressing the highlighted components have developed a placement algorithm for inserting microfluidic modules onto the biochip. After that, we inject runtime defects to simulate on biochip. Finally, we perform module reconfiguration to unused defect-free cells. 2.1 Microfluidic Module Library Performing...

With the growing interest in biochips, numerous efforts have been made to recapitulate a more reliable and physiologically relevant environment within chips, resulting significant advances biochip technologies. Although there substantial improvements fabrication technologies, less effort has devoted improving imaging or microscopic methods specialized for observing in-chip structures. As struct...

Rapid pathogen sensing remains a pressing issue today since conventional identification methodsare tedious, cost intensive and time consuming, typically requiring from 48 to 72 h. In turn, chip based technologies, such as microarrays and microfluidic biochips, offer real alternatives capable of filling this technological gap. In particular microfluidic biochips make the development of fast, sen...

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