A silicon microcantilever sensor was developed for the detection of Escherichia coli O157:H7. The microcantilever was modified by anti-E. coli O157:H7 antibodies on the silicon surface of the cantilever. When the aquaria E. coli O157:H7 positive sample is injected into the fluid cell where the microcantilever is held, the microcantilever bends upon the recognition of the E. coli O157:H7 antigen...

Microcantilever sensor technology has been steadily growing for the last 15 years. While we have gained a great amount of knowledge in microcantilever bending due to surface stress changes, which is a unique property of microcantilever sensors, we are still in the early stages of understanding the fundamental surface chemistries of surface-stress-based microcantilever sensors. In general, incre...

In microcantilever-based biosensor, a sensitive layer plays an important role as a place for the establishment of functional layer for detecting molecules target. When a sensitive layer is coated on the microcantilever surface, a surface stress change is induced as a consequence of adsorbate-surface interaction, resulting in a deflection of the microcantilever. However, the microcantilever with...

Microcantilever is a device of MEMS (microelectro-mechanical system) which can be used as bio-chemical sensor, such to determine the characteristics chemical liquids. In this work, an investigation evaporation rate liquids, i.e., ethanol, methanol, and propanol, was carried out using resonant frequency change vibrated microcantilever. We two types microcantilever, namely uncoated-microcantileve...

microcantilevers (mcls) are cost-effective and highly sensitive devices for biodetection. adsorption of specific analytes on the microcantilever surface causes the bending of mcl through changing of the surface characteristics. these new bioprobes designed in a way that one side of the microcantilever surface is coated with a selective receptor that absorbs particular molecules. after surface a...

We demonstrate a microcantilever array with an in-plane photonic transduction method for simultaneous readout of each microcantilever. The array is fabricated on a silicon-on-insulator substrate. Rib waveguides in conjunction with a compact waveguide splitter network comprised of trench-based splitters and trench-based bends route light from a single optical input to each microcantilever on the...

We review progress toward microcantilever arrays with in-plane photonic readout for biosensing applications. Microcantilever arrays are fabricated on individual silicon-on-insulator (SOI) chips and integrated with two-layer polydimethylsiloxane (PDMS) microfluidics that incorporate fluid channels and valves. Microcantilever functionalization is accomplished by inkjetting appropriate fluids onto...

Femtomolar concentrations of hydrogen fluoride, a decomposition component of nerve agents, were detected using a SiO(2) microcantilever. The microcantilever underwent bending due to the reaction of HF with SiO(2). The microcantilever deflection increased as the concentration of HF increased. Other acids, such as HCl, had no effect on the deflection of the cantilever. The mechanism of reaction-i...

We have investigated the sensing performance of protein-based microcantilever biosensors prepared from multiple surface conjugation chemistries. The 11-mercaptoundecanoic acid monolayers were prepared according to both traditional and modified processes. In three protein-based biosensors, the modified process improved microcantilever sensing performance by increasing the bending amplitude, a cr...

We present here a combined theoretical and experimental investigation on effective excitation of microcantilever by using photoacoustic waves. The photoacoustic waves arose from a vibrating Al foil induced by an intensity-modulated laser. We demonstrate that, superior to photothermal excitation, this new configuration avoids direct heating of the microcantilever, thus minimizing undesired therm...