نتایج جستجو برای: Methylxanthines

تعداد نتایج: 350  

Bibi Sedigheh Fazly Bazzaz, Hossein Hosseinzadeh, Mojgan Moaddab Sadati,

Background: The development of resistance to antimicrobial agents is a major problem in chemotherapy. Finding agents which potentiate antimicrobial activity could be favorable. There are some reports that methylxanthines changed the inhibitory effect of antibacterial agents. Thus, possible synergistic effect of methylxanthines, aminophylline and caffeine on some antibiotics, carbenicillin, ceft...

Journal: :Acta biochimica Polonica 2005
Jacek Piosik Anna Gwizdek-Wiśniewska Katarzyna Ulanowska Jakub Ochociński Agata Czyz Grzegorz Wegrzyn

Previously performed experiments showed that methylxanthines, especially caffeine, may protect cells against cytostatic or cytotoxic effects of several aromatic compounds. One of the proposed mechanisms of this protection is based on stacking interactions between pi electron systems of polycyclic aromatic molecules. In this work, we demonstrate that caffeine and other methylxanthines--pentoxify...

2010
Sohei Makino Makoto Fueki Naoto Fueki

Theophylline is a bronchodilator that also has an anti-inflammatory effect. In Japan, methylxanthines, including theophylline and aminophylline (theophylline ethylenediamine), have been used widely in the treatment of asthma. In some asthma management guidelines, although methylxanthines are recommend for the treatment of asthma, they are not preferred primarily because of potential serious adv...

Journal: :Science 1984
J A Nathanson

Natural and synthetic methylxanthines inhibit insect feeding and are pesticidal at concentrations known to occur in plants. These effects are due primarily to inhibition of phosphodiesterase activity and to an increase in intracellular cyclic adenosine monophosphate. At lower concentrations, methylxanthines are potent synergists of other pesticides known to activate adenylate cyclase in insects...

Journal: :iranian biomedical journal 0
حسین حسین زاده hossein hosseinzadeh بی بی صدیقه فضلی بزاز bibi sedigheh fazly bazzaz مژگان مؤدب ساداتی mojgan moaddab sadati

background: the development of resistance to antimicrobial agents is a major problem in chemotherapy. finding agents which potentiate antimicrobial activity could be favorable. there are some reports that methylxanthines changed the inhibitory effect of antibacterial agents. thus, possible synergistic effect of methylxanthines, aminophylline and caffeine on some antibiotics, carbenicillin, ceft...

2013
Rafael Franco Ainhoa Oñatibia-Astibia Eva Martínez-Pinilla

One may wonder why methylxanthines are so abundant in beverages used by humans for centuries, or in cola-drinks that have been heavily consumed since their appearance. It is likely that humans have stuck to any brew containing compounds with psychoactive properties, resulting in a better daily life, i.e., more efficient thinking, exploring, hunting, etc., however, without the serious side effec...

Journal: :The Cochrane database of systematic reviews 2005
A B Chang R A Halstead H L Petsky

BACKGROUND Non-specific cough is defined as non-productive cough in the absence of identifiable respiratory disease or known aetiology. It is commonly seen in paediatric practice. These children are treated with a variety of therapies including a variety of asthma medications. Methylxanthines, the main medication used for paediatric asthma for many decades in Western countries, is still widely ...

Journal: :Journal of Materials Chemistry C 2021

Simultaneous quantification of drug isomers, methylxanthines (MeX), by SERS via self-assembly gold nanoparticles (Au NPs) mediated cucurbit[ n ]urils (CBs).

Journal: :Molecules 2016
João P Monteiro Marco G Alves Pedro F Oliveira Branca M Silva

Methylxanthines are a group of phytochemicals derived from the purine base xanthine and obtained from plant secondary metabolism. They are unobtrusively included in daily diet in common products as coffee, tea, energetic drinks, or chocolate. Caffeine is by far the most studied methylxanthine either in animal or epidemiologic studies. Theophylline and theobromine are other relevant methylxanthi...

Journal: :American journal of physiology. Cell physiology 2012
Paola Ojeda Alejandra Pérez Lorena Ojeda Mauricio Vargas-Uribe Coralia I Rivas Monica Salas Juan Carlos Vera Alejandro M Reyes

Glucose transporter (GLUT)1 has become an attractive target to block glucose uptake in malignant cells since most cancer cells overexpress GLUT1 and are sensitive to glucose deprivation. Methylxanthines are natural compounds that inhibit glucose uptake; however, the mechanism of inhibition remains unknown. Here, we used a combination of binding and glucose transport kinetic assays to analyze in...

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