BACKGROUND Medications with methyl-prednisolone sodium succinate containing lactose, which potentially contains traces of cow's milk proteins (CMP), could cause allergic reactions or compromise treatment of acute allergic reactions in sensitized patients. CASE PRESENTATION We describe the unusual case of a one-year-old child affected by short bowel syndrome and history of severe cow's milk al...

In this prospective study the effect of low dose methylprednisolone succinate (10mg/kg) on the incidence of fat embolism syndrome and isolated arterial hypoxemia in 99 patients with long bone fracture (52 control and 47 steroid-trated subjects) was studied. Frequency of fractures among the selected patients was as follows: femoral fracture 52.5%, tibial fracture 36.4%, both femoral and tibial f...

INTRODUCTION Immediate-type hypersensitivity to glucocorticosteroids is rare but well known among allergists. Surprisingly, very few reports of glucocorticosteroid hypersensitivity in children exist although glucocorticosteroid treatment is particularly common in this age group. CASE PRESENTATION We report the case of a 2-year-old boy who developed generalized urticaria, facial angio-oedema, ...

objective(s): to study the effect of cardiopulmonary bypass (cpb) on nuclear factor-kappa b (nf-кb) and cytokine expression and pulmonary function in dogs. materials and methods: twelve male mongrel dogs were divided into a methylprednisolone group (group m) and a control group (group c). all animals underwent aortic and right atrial catheterization under general anesthesia. changes in pulmonar...

Glucocorticoids are frequently used to treat allergic reactions. Therefore, allergic reactions to systemic glucocorticoids in particular are considered most unlikely and are not well known. We report on a 23-year-old woman with atopic dermatitis who had an anaphylactic reaction after oral administration of prednisolone. On treatment with epinephrine, antihistamines and volume symptoms resolved....

purpose : to evaluate the therapeutic effect of posterior sub-tenon methyl prednisolone in anterior ischemic optic neuropathy, no class 1 study has shown any conclusive medical or surgical treatment for non-arteritic anterior ischemic optic neuropathy (naion). efficacy of systemic or intravitreal steroids was suggested by some studies. this study was performed to evaluate the efficacy and safet...

IN recent years synthetic analogues of cortisone and hydrocortisone have been employed in the treatment of rheumatoid arthritis. Prednisone and prednisolone were first used by Bunim, Pechet, and Bollet in 1955, and since then further reports Although the greater anti-rheumatic effects and lessened risks of sodium retention in these compounds have been advantageous, most workers have been concer...

PURPOSE To evaluate the role of intravenous methyl prednisolone in patients with solitary cysticercus granuloma with new-onset seizures. METHODS In this open-label, randomized, prospective, follow-up study, 52 patients with new-onset seizures and a single enhancing CT lesion of cysticercus were randomly divided in two groups to receive either intravenous methyl prednisolone for 5 days along w...

Purpose: The aim of this study was to examine the protective effects of nonsteroid anti-inflammatory drugs (NSAIDs) and steroids on seroma formation after mastectomy and axillary lymph node dissection in rats. Methods: Mastectomy and axillary lymph node dissection were applied to the rats. Thirty rats enrolled in the study were randomly divided into three groups of 10 each. Group I patients rec...