Solid dispersion is molecular dispersion of drug in a polymer matrix which leads to improved solubility and hence better bioavailability. Solvent evaporation technique was employed to prepare films of different combinations of polymers, plasticizer, and a modal drug sulindac to narrow down on a few polymer-plasticizer-sulindac combinations. The sulindac-polymer-plasticizer combination that was ...

This paper presents the preparation and mechanical properties of compatibilized compositionally graded Polyethylene/ low density polyethylene (LDPE)/ modified montmorillonite (MMT) nanocomposites prepared by solution and melt mixing techniques. Use of polyethylene glycol as compatibilizer improves compatibility of modified montmorillonite and low density polyethylene.  Comparisons between two t...

Water-assisted, or more generally liquid-mediated, melt compounding of nanocomposites is basically a combination of solution-assisted and traditional melt mixing methods. It is an emerging technique to overcome several disadvantages of the above two. Water or aqueous liquids with additives, do not work merely as temporary carrier materials of suitable nanofillers. During batchwise and continuou...

Abstract Graphene Oxide (GO) was added to Low-Density Polyethylene (LDPE) test the mechanical properties of compound. Compared other types polyethylene, LDPE provides a good balance and processability, which leads its being chosen as research’s matrix material. This experiment aims prepare LDPE/GO through melt mixing technique analyse tensile strength/tensile elongation composite based on GO co...

We have applied a novel 'melt synthesis technique' rather than a conventional solid-state reaction to rapidly synthesize phosphor materials. During a synthesis, the mixture of oxides or their precursors is melted by light pulses (10-60 s) in an arc-imaging furnace on a water-cooled copper hearth to form a globule of 1-5 mm diameter, which is then rapidly cooled by turning off the light. Using t...

conclusions detection of drug resistance associated with mutations through real-time pcr by melting analysis technique showed a high differentiating power. this technique had high concordance with the standard proportion test and mas-pcr results. patients and methods in a cross-sectional study carried out in 2014, 90 patients with m. tuberculosis from five border provinces of iran were selected...

The influence of the morphology of industrial graphite nanoplate (GNP) materials on their dispersion in polycarbonate (PC) is studied. Three GNP morphology types were identified, namely lamellar, fragmented or compact structure. The dispersion evolution of all GNP types in PC is similar with varying melt temperature, screw speed, or mixing time during melt mixing. Increased shear stress reduces...

Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...

This work focused on the influence of processing conditions on the mechanical properties of polypropylene (PP) and PP/mesoporous silica-hydroxyapatite (PP/MCM-41-HA) hybrid nanocomposites. The mechanical properties of PP were enhanced by adding MCM-41-HA nanoparticles. Neat PP and hybrid nanocomposites based on PP, containing maleic anhydride-grafted polypropylene (PP-g-MA) and MCM-41-HA, were ...

This study treats one important aspect of starch-filled rubber compounds which is their rheological behavior. Starch-based SBR1712 masterbatches resulting from various formulations were prepared using a mini two roll mill and an internal mixer (Plastograph Brabender).The content in starch was varied from 0 to 50 phr. The effect of starch content on the rheological behavior was ev...