statement of the problem melatonin has powerful antioxidant effects, has an immunomodulatory role, stimulates the synthesis of type i collagen fibers, and promotes bone formation. melatonin is also secreted in the saliva, although its role in the mouth is not known well purpose the aim of this study was to examine the correlation between salivary melatonin level and periodontal diseases materia...

background: infertility is defined as the inability to achieve the pregnancy within a year of unprotected intercourse. infertility is a complex issue and different factors such as stress oxidative can be involved in this problem. so, any attempt to neutralize oxidative stress would be helpful in the treatment of infertility. melatonin is a known scavenger of free radicals. objective: the aim of...

objectives:vagal pathways in gastrointestinal tract are the most important pathways that regulate ischemia/reperfusion (i/r).  gastrointestinal tract is one of the important sources of melatonin production. the aim of this study was to investigate probable protective effect of the interaction between vagus nerve and melatonin after i/r. materials and methods:this study was performed in male rat...

background: after radiation therapy (rt), some health hazards including dna damages may occur where melatonin can play a protective role due to free radical generation. on the other hand, serious accidental overexposures may occur during rt due to nuclear accidents which necessitate the need for study on exposure to high-dose radiations during treatments. objective: the aim of this study was to...

background and aims. melatonin is a circulating hormone that is mainly released from the pineal gland. it possesses antioxidant, free-radical scavenging, and immune-enhancing properties. a growing number of studies reveal a complex role for melatonin in influencing various diseases, including diabetes and periodontal diseases. the aim of this study was to examine the possible links between sali...

Background: This study investigates the effects of melatonin on the sperm quality, the level of antioxidant enzymes (TAC) and malondialdehyde (MDA) after the combination of swimming exercise and nandrolone decanoate (DECA). Materials and Methods: Two groups of male Wistar rats were treated for eight weeks as follows; group A consist of: CO (control), Sham, N (DECA), S (swimming) and NS (DECA pl...

melatonin has both pro-inflammatory and anti-inflammatory properties depending on the stage of inflammation. despite its therapeutic effect in alleviation of some symptoms of multiple sclerosis; the precise role of melatonin in ms pathogenesis remains a topic of debate. the aim of this study was to measure the urine level of one of melatonin products which is an index of serum melatonin level, ...

several studies have reported that the antioxidant properties of melatonin can provide cardiac protection through scavenging of free radicals. this study sought to investigate the efficacy of melatonin on cardiac biomarkers, myocardial-specific protein high sensitive troponin-t (hs-tnt) and creatine kinase-mb (ck-mb), in patients with st-segment elevation myocardial infarction (stemi) undergoin...