background and objectives: colocynthin is the major active secondary metabolite of colocynth, citrullus colocynthis (l.) schrad, which has been used in traditional and ethno medicine of many countries.  it could be considered as an active marker for quality control of colocynth and its herbal products. analysis and standardization of colocynth and its herbal preparations are a critical issue fo...

A review of the many uses of matrix solid phase dispersion (MSPD) in the extraction and analysis of a variety of compounds from a range of samples is provided. Matrix solid phase dispersion (MSPD) has found particular application as a somewhat generic analytical process for the preparation, extraction and fractionation of solid, semi-solid and/or highly viscous biological samples. Its simplicit...

The present work involves numerical simulation of a steady, incompressible forcedconvection fluid flow through a matrix of porous media between two parallel plates at constanttemperature. A Darcy model for the momentum equation was employed. The mathematical model forenergy transport was based on single phase equation model which assumes local thermal equilibriumbetween fluid and solid phases. ...

Background and objectives: Carvacrol is one of the main pharmacologically active components of Thymus vulgaris essential oil which has shown several therapeutic effects. There are few works regarding the formulation of essential oils as oral solid dosage forms due to their liquid nature, stability and technical problems. The aim of this study was to combine the solid-d...

aim: to enhance the aqueous solubility of olanzapine by using the solid dispersion technique. solid dispersions of olanzapine were prepared by the dispersion method using using pgs and ssg as carriers. drug:carrier ratios such as 1:1, 1:2, 1:4, 1:6, 1:8 and 1:10 were tried for optimization. characterization was done by phase solubility, in vitro release, saturation solubility, permeation, wetta...

an extraction method based on matrix solid phase dispersion (mspd) and high performance liquid chromatography with uv detection for quantification of two widely used pesticides (malathion and α-endosulfan) in khazar rice from north of iran were investigated. the ratio of solid phase (adsorbent) to sample, types of eluting solvent and its volume were optimized to achieve the highest recoveries f...