نتایج جستجو برای: Mard-abad granite

تعداد نتایج: 6373  

Journal: :journal of sciences, islamic republic of iran 2014
z. salehi

mard-abad calc-alkaline granite formed along the margin of active pull-apart or intra-continental plates, and it is post-collision granite type. granophyric, perthitic and myrmekitic are main textures that could form from crystallization of hypersolvus source magma, which occurred under water vapor pressure of approximately 2 kb. during this study the temperature of formation of these granites ...

Z. Salehi

Mard-abad calc-alkaline granite formed along the margin of active pull-apart or intra-continental plates, and it is post-collision granite type. Granophyric, perthitic and myrmekitic are main textures that could form from crystallization of hypersolvus source magma, which occurred under water vapor pressure of approximately 2 kb. During this study the temperature of formation of these granites ...

Journal: :Journal of diabetes science and technology 2013
Stefan Pleus Christina Schmid Manuela Link Eva Zschornack Hans-Martin Klötzer Cornelia Haug Guido Freckmann

BACKGROUND This study aimed at evaluating and comparing the performance of a new generation of continuous glucose monitoring (CGM) system versus other CGM systems, under daily lifelike conditions. METHODS A total of 10 subjects (7 female) were enrolled in this study. Each subject wore two Dexcom G4™ CGM systems in parallel for the sensor lifetime specified by the manufacturer (7 days) to allo...

2015
Nancy Dunne Maria T. Viggiani Scott Pardo Cynthia Robinson Joan Lee Parkes

INTRODUCTION The aim of this study was to compare the accuracy of 5 blood glucose monitoring systems (BGMSs; CONTOUR(®)PLUS [CP], Accu-Chek(®) Active [ACA], Accu-Chek(®) Performa [ACP], FreeStyle Freedom™ [FF], OneTouch(®) SelectSimple™ [OTSS]). METHODS Study staff tested fingerstick samples from 106 subjects aged ≥18 years using the 5 BGMSs. Some samples were modified to achieve blood glucos...

Journal: :Journal of diabetes science and technology 2013
Solveig Halldorsdottir Mary Ellen Warchal-Windham Jane F Wallace Scott Pardo Joan Lee Parkes David A Simmons

BACKGROUND This study evaluated differences in accuracy between the CONTOUR® NEXT EZ (EZ) blood glucose monitoring system (BGMS) and four other BGMSs [ACCU-CHEK® Aviva (ACAP), FreeStyle Freedom Lite® (FFL), ONE TOUCH® Ultra®2 (OTU2), and TRUEtrack® (TT)]. METHODS Up to three capillary blood samples (N = 393) were collected from 146 subjects with and without diabetes. One sample per subject wa...

Journal: :Science 2004
Joyce W Lustbader Maurizio Cirilli Chang Lin Hong Wei Xu Kazuhiro Takuma Ning Wang Casper Caspersen Xi Chen Susan Pollak Michael Chaney Fabrizio Trinchese Shumin Liu Frank Gunn-Moore Lih-Fen Lue Douglas G Walker Periannan Kuppusamy Zay L Zewier Ottavio Arancio David Stern Shirley ShiDu Yan Hao Wu

Mitochondrial dysfunction is a hallmark of beta-amyloid (Abeta)-induced neuronal toxicity in Alzheimer's disease (AD). Here, we demonstrate that Abeta-binding alcohol dehydrogenase (ABAD) is a direct molecular link from Abeta to mitochondrial toxicity. Abeta interacts with ABAD in the mitochondria of AD patients and transgenic mice. The crystal structure of Abeta-bound ABAD shows substantial de...

2013
Xu Wang Yi Yang Mingyue Jia Chi Ma Mingyu Wang Lihe Che Yu Yang Jiang Wu

Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredoxin (TRX) using molecular cloning technique to construct a fusion gene that can express the TRX1-A...

Journal: :Current Alzheimer research 2014
Koteswara R Valaasani Qinru Sun Gang Hu Jianping Li Fang Du Yaopeng Guo Emily A Carlson Xueqi Gan Shirley S Yan

Amyloid beta (Aβ) binding alcohol dehydrogenase (ABAD) is a cellular cofactor for promoting (Aβ)-mediated mitochondrial and neuronal dysfunction, and cognitive decline in transgenic Alzheimer's disease (AD) mouse models. Targeting mitochondrial ABAD may represent a novel therapeutic strategy against AD. Here, we report the biological activity of small molecule ABAD inhibitors. Using in vitro su...

Journal: :Journal of diabetes science and technology 2013
Eva Zschornack Christina Schmid Stefan Pleus Manuela Link Hans-Martin Klötzer Karin Obermaier Michael Schoemaker Monika Strasser Gerhard Frisch Günther Schmelzeisen-Redeker Cornelia Haug Guido Freckmann

BACKGROUND The performance of a continuous glucose monitoring (CGM) system in the early stage of development was assessed in an inpatient setting that simulates daily life conditions of people with diabetes. Performance was evaluated at low glycemic, euglycemic, and high glycemic ranges as well as during phases with rapid glucose excursions. METHODS Each of the 30 participants with type 1 dia...

Journal: :Journal of diabetes science and technology 2007
Sharbel E Noujaim David Horwitz Manoj Sharma Joseph Marhoul

BACKGROUND There has been considerable debate on what constitutes a good hypoglycemia (Hypo) detector and what is the accuracy required from the continuous monitoring sensor to meet the requirements of such a detector. The performance of most continuous monitoring sensors today is characterized by the mean absolute relative difference (MARD), whereas Hypo detectors are characterized by the numb...

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