effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. as a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. the fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose con...

in this paper, we present a simulated annealing (sa) and a genetic algorithm (ga) based on heuristics for scheduling problem of jobs in virtual cellular manufacturing systems. a virtual manufacturing cell (vmc) is a group of resources that is dedicated to the manufacturing of a part family. although this grouping is not reflected in the physical structure of the manufacturing system, but machin...

ii Manufacturing strategy formulation in small and medium-sized enterprises MALIN LÖFVING Doktorsavhandlingar vid Chalmers tekniska högskola Ny serie nr 3689 ISSN 0346 – 718X ABSTRACT Small and medium-sized enterprises (SMEs) are the backbone of any national economy and key drivers for economic growth. To sustain their competitiveness, it is essential that SMEs take advantage of their capabilit...

The paper discusses how the calibration and use of a Computer Based Learning Environment (CBLE), which is based on a system dynamics model, can form the basis of strategy formulation processes at the operations level. The rationale behind, the structure and the elements of the SYDMAS CBLE, as well as its embedment in a scenario-driven manufacturing strategy formulation process are presented. Th...

Effects of formulation parameters on the fractional release profile of diclofenac sodium from matrices having the manufacturing formulation ingredients are studied. As a content of cetyl alcohol (rate controlling agent) in the matrix increases, the fractional release decreases. The fractional release increases either by increasing sucrose content outside the granule or by decreasing sucrose...

Purpose: The paper aims at increasing the understanding of how manufacturing strategy formulation can be facilitated in SMEs. Design/methodology/approach: The research presented in this paper follows a four-stage logic. Initially a literature review was conducted identifying a number of manufacturing strategy frameworks. Thereafter, theoretical and practical assessment criteria were established...

A mathematical framework which has been speci cally developed for manufacturing-like systems is presented, focusing on time-free dynamics and control, as treated by Finite State Automata. The approach is based on the key concepts of object types, locations and manufacturing operations enriched with an algebra (Manufacturing Algebra) for building complex operations as algebraic series-parallel c...