نتایج جستجو برای: Mantle Cell Lymphoma

تعداد نتایج: 1735749  

Journal: Iranian Journal of Pathology 2012
Koyye Ravindranath Tagore, Ramineni S Asok Kumar

Mantle cell lymphoma is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. The gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. Multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...

متن کامل
Journal: :iranian journal of pathology 2012
koyye ravindranath tagore ramineni s asok kumar

mantle cell lymphoma is an aggressive type of b-cell non-hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node. the gastrointestinal tract is the predominant site of extranodal involvement in the form of multiple lymphomatous polyposis. multiple lymphomatous polyposis due to mantle cell lymphoma presenting with intussusception is ...

متن کامل
Journal: :Haematologica 2012
Daniel J Medina Lauri Goodell John Glod Céline Gélinas Arnold B Rabson Roger K Strair

BACKGROUND There is increasing evidence that stromal cell interactions are required for the survival and drug resistance of several types of B-cell malignancies. There is relatively little information regarding the role of the bone marrow/lymphoid microenvironment in the pathogenesis of mantle cell lymphoma. In this study we investigated the interaction of primary mantle cell lymphoma cells wit...

متن کامل
Journal: :Haematologica 2009
Ana Mozos Cristina Royo Elena Hartmann Daphne De Jong Cristina Baró Alexandra Valera Kai Fu Dennis D Weisenburger Jan Delabie Shih-Sung Chuang Elaine S Jaffe Carmen Ruiz-Marcellan Sandeep Dave Lisa Rimsza Rita Braziel Randy D Gascoyne Francisco Solé Armando López-Guillermo Dolors Colomer Louis M Staudt Andreas Rosenwald German Ott Pedro Jares Elias Campo

BACKGROUND Cyclin D1-negative mantle cell lymphoma is difficult to distinguish from other small B-cell lymphomas. The clinical and pathological characteristics of patients with this form of lymphoma have not been well defined. Overexpression of the transcription factor SOX11 has been observed in conventional mantle cell lymphoma. The aim of this study was to determine whether this gene is expre...

متن کامل
Journal: :Haematologica 2013
Lijuan Wang Jianfei Qian Yong Lu Haiyan Li Hanying Bao Donghua He Zhiqiang Liu Yuhuan Zheng Jin He Yi Li Sattva Neelapu Jing Yang Larry W Kwak Qing Yi Zhen Cai

Clinical trials of immunotherapy in mantle cell lymphoma have not yet delivered desirable results, partly because of the inhibitory machinery of the tumor and its microenvironment. Here we investigated the role of B7-H1, a member of the B7 family of co-stimulatory/co-inhibitory ligands, in mantle cell lymphoma-mediated immunosuppression. Allogeneic CD3(+), CD4(+) and CD8(+) T cells were purifie...

متن کامل
Journal: :Haematologica 2012
Alejandra Carvajal-Cuenca Luz F Sua Nhora M Silva Stefania Pittaluga Cristina Royo Joo Y Song Rachel L Sargent Blanca Espinet Fina Climent Samuel A Jacobs Jan Delabie Kikkeri N Naresh Adam Bagg Pierre Brousset Roger A Warnke Sergi Serrano Nancy Lee Harris Steven H Swerdlow Elaine S Jaffe Elías Campo

BACKGROUND Cyclin D1-positive B cells are occasionally found in the mantle zones of reactive lymphoid follicles, a condition that has been called "in situ mantle cell lymphoma". The clinical significance of this lesion remains uncertain. DESIGN AND METHODS The clinical and pathological characteristics, including SOX11 expression, of 23 cases initially diagnosed as in situ mantle cell lymphoma...

متن کامل
2018
Martina Rudelius Mathias Tillmann Rosenfeldt Ellen Leich Hilka Rauert-Wunderlich Antonio Giovanni Solimando Andreas Beilhack German Ott Andreas Rosenwald

Mantle cell lymphoma and other lymphoma subtypes often spread to the bone marrow, and stromal interactions mediated by focal adhesion kinase frequently enhance survival and drug resistance of the lymphoma cells. To study the role of focal adhesion kinase in mantle cell lymphoma, immunohistochemistry of primary cases and functional analysis of mantle cell lymphoma cell lines and primary mantle c...

متن کامل
Journal: :iranian red crescent medical journal 0
a bahari department of gastroenterology, mashhad university of medical sciences, iran m jahantigh department of pathology, zahedan university of medical sciences, iran a mashhadi department of hematology and oncology, zahedan university of medical sciences, iran z bari department of internal medicine, zahedan university of medical sciences, iran 989111536575, zohreb252@yahoo.com; department of internal medicine, zahedan university of medical sciences, iran 989111536575, zohreb252@yahoo.com ar bari department of hematology and oncology, shariati hospital, tehran university of medical sciences, iran

background plasmablastic lymphoma (pbl) is a relatively new entity, classified by who as a rare variant of diffuse large b cell lymphoma. the present case report introduces a 17 year old girl with chronic diarrhea, abdominal pain, intra-abdominal venous thromboses, ascites, mesenteric lymphadenopathies and small intestinal polyposis, the pathologic and immunohistochemistric examinations of the ...

متن کامل
Journal: :IP archives of cytology and histopathology research 2021

: Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of non-Hodgkin's (NHL), characterized by poor outcome, accounting approximately for 10%-15% all non-Hodgkin in the western countries, and with higher prevalence Asia. Cyclin D1 immunoreactivity is characteristically seen mantle cell lymphoma. It also observed hairy leukemia, plasma myeloma proportion diffuse large B-cell lymp...

متن کامل
Journal: :Acta histochemica 2011
Sarah E Henson Travis Morford Mary-Pat Stein Randolph Wall Cindy S Malone

Mantle cell lymphoma and small lymphocytic lymphoma are lymphocyte cancers that have similar morphologies and a common age of onset. Mantle cell lymphoma is generally an aggressive B cell lymphoma with a short median survival time, whereas small lymphocytic lymphoma is typically an indolent B cell lymphoma with a prolonged median survival time. Using primary tumor samples in bi-directional supp...

متن کامل

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید

function paginate(evt) { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term pg=parseInt(evt.target.text) var data={ "year":filter_year, "term":term, "pgn":pg } filtered_res=post_and_fetch(data,url) window.scrollTo(0,0); } function update_search_meta(search_meta) { meta_place=document.getElementById("search_meta_data") term=search_meta.term active_pgn=search_meta.pgn num_res=search_meta.num_res num_pages=search_meta.num_pages year=search_meta.year meta_place.dataset.term=term meta_place.dataset.page=active_pgn meta_place.dataset.num_res=num_res meta_place.dataset.num_pages=num_pages meta_place.dataset.year=year document.getElementById("num_result_place").innerHTML=num_res if (year !== "unfilter"){ document.getElementById("year_filter_label").style="display:inline;" document.getElementById("year_filter_place").innerHTML=year }else { document.getElementById("year_filter_label").style="display:none;" document.getElementById("year_filter_place").innerHTML="" } } function update_pagination() { search_meta_place=document.getElementById('search_meta_data') num_pages=search_meta_place.dataset.num_pages; active_pgn=parseInt(search_meta_place.dataset.page); document.getElementById("pgn-ul").innerHTML=""; pgn_html=""; for (i = 1; i <= num_pages; i++){ if (i===active_pgn){ actv="active" }else {actv=""} pgn_li="
  • " +i+ "
    • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->