background: major depression disorder (mdd) is a common disorder with preva-lence of 15% among men and up to 25% among women. in recent years the association of immune system alterations and mdd has been investigated. assessments of immu-nologic and inflammatory responses in these patients enhance our knowledge of the eti-ology and pathogenesis of this disease. objective: to investigate the cha...

Background: Major Depression Disorder (MDD) is a common disorder with preva-lence of 15% among men and up to 25% among women. In recent years the association of immune system alterations and MDD has been investigated. Assessments of immu-nologic and inflammatory responses in these patients enhance our knowledge of the eti-ology and pathogenesis of this disease. Objective: To investigate the cha...

Objectives: A correlation between hyperhomocysteinemia, and depression has been reported. Saffron (Crocus sativus) is recommended for treatment of depression; hence, in this study the effect of co-administration of saffron and fluoxetine on plasma homocysteine and depression was evaluated. Material and methods: This was a 4-week randomized and double-blind clinical trial which was conducted fro...

abstract aim and background: theory of mind is the ability to attribute one’s own or others mental states which has an important role in social and behavioral performances. the purpose of the present study was compare theory of mind in patients with schizophrenia and major depression with normal individuals. methods and materials: the present research was a causal- comparative study. the subjec...

the current study was performed with the aim of investigating the diagnostic utility of bender-gestalt test-ii (bdt-ii) in two groups of patients with major depression and brain-damage, and to compare them with normal individuals. this was a causal-comparative study. major depressive patients (n=30), brain-damaged patients (n=30) and normal subjects (n=30) were compared using bdt-ii in copying,...

OBJECTIVE To overview limitations to the concept and construct of major depression. METHOD The objectives in initially conceptualizing major depression are examined against its subsequent utility and relevance to clinicians and researchers. RESULTS It is argued that, as defined, major depression does not differentiate clinical depression well from expressions of non-clinical depression or s...

BACKGROUND Previous cross-sectional study showed altruistic behaviors were harmful on major depression (MD). It is needed to investigate the impact of altruistic behaviors by its contents on the development of MD prospectively. METHODOLOGY/PRINCIPAL FINDINGS The National Survey of Midlife Development in the United States (MIDUS) in 1995-1996 and the MIDUS Psychological Experience Follow-Up st...

PURPOSE There is currently little information about rates of positive maternal depression screens immediately after delivery; rather, most studies have assessed the prevalence of major depression between 1 and 6 months postpartum. This study investigated the rate of positive 9-item Patient Health Questionnaire (PHQ-9) surveys within 1 to 2 days after delivery. METHODS A retrospective chart re...