نتایج جستجو برای: Magnetization Transfer Ratio (MTR)

تعداد نتایج: 795318  

Journal: :iranian journal of medical physics 0
masoomeh fooladi m.sc. in medical physics, medical physics and biomedical engineering dept., tehran university of medical sciences, tehran, iran nader riahi alam associate professor, medical physics and biomedical engineering dept., tehran university of medical sciences, tehran, iran mohammad hossein harirchyan associate professor, neurology dept., tehran university of medical sciences, tehran, iran kavoos firuznia associate professor, radiology dept., tehran university of medical sciences, tehran, iran mohammad ali oghabian associate professor, medical physics and biomedical engineering dept., tehran university of medical sciences, tehran, iran majid shakiba researcher, medical imaging research center, imam khomeini hospital, tehran university of medical sciences, tehran, iran

introduction: multiple sclerosis (ms) is a demyelinating disease of the central nervous system (cns), affecting mostly young people at a mean age of 30 years. magnetic resonance imaging (mri) is one of the most specific and sensitive methods in diagnosing and detecting the evolution of multiple sclerosis disease. but it does not have the ability to differentiate between distinct histopathologic...

Journal: :Neurology 1997
S E Kasner S L Galetta J C McGowan R I Grossman

We report a patient with biopsy-proven progressive multifocal leukoencephalopathy (PML) who was serially imaged with MRI and magnetization transfer imaging. The magnetization transfer ratio (MTR) was profoundly and significantly diminished when compared with normal control subjects. The pattern of MTR was distinct from that of MS and periventricular ischemic white matter disease. Magnetization ...

2015
Jae-Woong Kim Jiye Choi Janggeun Cho Chulhyun Lee Daejong Jeon Sung-Hong Park

Magnetization transfer ratio (MTR) has been often used for imaging myelination. Despite its high sensitivity, the specificity of MTR to myelination is not high because tissues with no myelin such as muscle can also show high MTR. In this study, we propose a new magnetization transfer (MT) indicator, MT asymmetry (MTA), as a new method of myelin imaging. The experiments were performed on rat bra...

Behrooz Rafie Kavoos Firuznia Majid Shakiba Masoomeh Fooladi Mohammad Ali Oghabian, Mohammad Hossein Harirchyan Morteza Bakhtiary Nader Riahi Alam

Introduction: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS), affecting mostly young people at a mean age of 30 years. Magnetic resonance imaging (MRI) is one of the most specific and sensitive methods in diagnosing and detecting the evolution of multiple sclerosis disease. But it does not have the ability to differentiate between distinct histopathologic...

Journal: :AJNR. American journal of neuroradiology 2000
S Ropele S Strasser-Fuchs M Augustin R Stollberger C Enzinger H P Hartung F Fazekas

BACKGROUND AND PURPOSE Magnetization transfer (MT) imaging and measurements of the magnetization transfer ratio (MTR) have extended our capability to depict and characterize pathologic changes associated with multiple sclerosis (MS). We wanted to investigate whether the analysis of other MT parameters, such as magnetization transfer rate (k(for)) and relative measure of water content (T1(free))...

2014
Stephan Seiler Lukas Pirpamer Edith Hofer Marco Duering Eric Jouvent Franz Fazekas Jean-Francois Mangin Hugues Chabriat Martin Dichgans Stefan Ropele Reinhold Schmidt

Magnetization transfer imaging (MTI) can detect microstructural brain tissue changes and may be helpful in determining age-related cerebral damage. We investigated the association between the magnetization transfer ratio (MTR) in gray and white matter (WM) and cognitive functioning in 355 participants of the Austrian stroke prevention family study (ASPS-Fam) aged 38-86 years. MTR maps were gene...

Journal: :AJNR. American journal of neuroradiology 2001
M A van Buchem S C Steens H A Vrooman A H Zwinderman J C McGowan M Rassek V Engelbrecht

BACKGROUND AND PURPOSE In the developing brain, myelination occurs in an orderly and predetermined sequence. The aim of this study was to determine whether such changes can be tracked using volumetric magnetization transfer imaging. METHODS Three-dimensional magnetization transfer imaging was performed in 50 children (age range, 0.6-190 months) with no evidence of developmental delay or struc...

Journal: :AJNR. American journal of neuroradiology 1995
J F Hiehle R I Grossman K N Ramer F Gonzalez-Scarano J A Cohen

PURPOSE To define the relationship between magnetization transfer and blood-brain-barrier breakdown in multiple sclerosis lesions using gadolinium enhancement as an index of the latter. METHODS Two hundred twenty lesions (high-signal abnormalities on T2-weighted images) in 35 multiple sclerosis patients were studied with gadolinium-enhanced spin-echo imaging and magnetization transfer. Lesion...

Journal: :AJNR. American journal of neuroradiology 1996
H Kimura R I Grossman R E Lenkinski F Gonzalez-Scarano

PURPOSE To characterize plaques of multiple sclerosis (MS) using both proton MR spectroscopy and magnetization transfer (MT) imaging. METHODS The magnetization transfer ratio (MTR) was calculated from two series of three-dimensional gradient-recalled acquisition in the steady state (GRASS) images obtained with and without an MT saturation pulse. Proton spectra were acquired using the point-re...

Journal: :Hormones 2003
Maria I Argyropoulou Dimitrios Nikiforos Kiortsis

Magnetization transfer (MT) techniques provide tissue contrast which depends mainly on the concentration of macromolecules. The magnetization transfer phenomenon is determined by the restricted macromolecular protons and is quantified by the magnetization transfer ratio (MTR). Since many macromolecular structures are implicated in the secretory activity of the pituitary gland, this imaging tech...

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