نتایج جستجو برای: Macrolide antibiotics

تعداد نتایج: 72512  

Journal: :Journal of Antimicrobial Chemotherapy 2002

Journal: :iranian journal of basic medical sciences 0
amir farshchi school of pharmacy, kermanshah university of medical sciences, kermanshah, iran young researchers club, islamic azad university, kermanshah branch, iran golbarg ghiasi school of pharmacy, kermanshah university of medical sciences, kermanshah, iran young researchers club, islamic azad university, kermanshah branch, iran gholamreza bahrami school of pharmacy, kermanshah university of medical sciences, kermanshah, iran medical biology research center, kermanshah university of medical sciences, kermanshah, iran

objective(s) a sensitive liquid chromatographic method for the analysis of clarithromycin- a macrolide antibiotic- in human serum, using pre-column derivatization with 9-fluorenylmethyl chloroformate (fmoc-cl) is described. materials and methods the method involved liquid-liquid extraction of the drug and an internal standard (amantadine) followed by pre-column derivatization of the analytes wi...

Journal: :The Journal of Antibiotics 1989

2009
A Kamemoto T Ara T Hattori Y Fujinami Y Imamura P-L Wang

OBJECTIVE Macrolide antibiotics are reported to modulate the production of cytokines in various type of cells. We examined the effect of macrolide antibiotics on inflammatory cytokines (IL-6 and IL-8) and chemical mediator (PGE(2)) and also matrix metalloproteinases (MMPs) productions by human gingival fibroblasts (HGFs) treated with lipopolysaccharide (LPS). METHODS The effect of macrolide a...

Journal: :Mediators of Inflammation 2003
Hajime Terao Kazuhito Asano Ken-ichi Kanai Yoshiyuki Kyo So Watanabe Tadashi Hisamitsu Harumi Suzaki

BACKGROUND Low-dose and long-term administration of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including nitric oxide (NO), are well recognized as the important final effector molecules in the development and the...

Journal: :Environmental Health Perspectives 2002
Hajime Terao Kazuhito Asano Ken-ichi Kanai Tadashi Hisamitsu Harumi Suzaki

of macrolide antibiotics into patients with chronic airway inflammatory diseases could favorably modify their clinical conditions. However, the therapeutic mode of action of macrolides is not well understood. Free oxygen radicals, including nitric oxide (NO), are well recognized as the important final effector molecules in the development and the maintenance of inflammatory diseases. Purpose: T...

Journal: :The Journal of antibiotics 1995
T Ishii T Hida S Iinuma M Muroi Y Nozaki

We detected potent angiostatic activity in a MeOH extract from the mycelia of microbial strain S-45628 in the chick chorioallantoic membrane (CAM) assay. The producer was taxonomically characterized as Streptomyces purpurascens. Active principles designated TAN-1323 A-D were isolated and determined to be 18-membered macrolide antibiotics; components C and D are new members of this group, while ...

Journal: :Journal of Biological Chemistry 2000

Journal: :Cochrane Database of Systematic Reviews 2018

Journal: :Postgraduate Medical Journal 1979

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