نتایج جستجو برای: Macrofollicular

تعداد نتایج: 33  

2014
Varlık Erol Özer Makay Yeşim Ertan Gökhan İçöz Mahir Akyıldız Mustafa Yılmaz

Objective. The main aim of this study was to comparatively analyze the recurrence and prognosis of this rare variant with the literature by analyzing the follow-up data of 5 patients diagnosed with papillary cancer macrofollicular variant. Methods. The demographic data, radiological and pathological data, and prognostic data of 5 patients who underwent surgery for thyroid cancer and were diagno...

2011
Raddaoui Emad Arafah Maha Hala K. Kfoury Abdul Malik Al-Sheikh Shaesta N. Zaidi

The macrofollicular variant of papillary thyroid carcinoma (MFPTC) is a well-established entity with characteristic large follicles containing pale colloid and lined by cells with nuclear features of papillary thyroid carcinoma (PTC). In this study, we present three cases of MFPTC, along with a brief review of the literature. For all three of our cases, the histology of the resected specimen sh...

Journal: :Endocrine journal 2009
Mitsuhiro Fukushima Yasuhiro Ito Mitsuyoshi Hirokawa Kaoru Kobayashi Akihiro Miya Yuuki Takamura Haruki Akasu Kazuo Shimizu Akira Miyauchi

Macrofollicular variant is a rare entity of papillary carcinoma. We previously demonstrated that this variant accounts for 0.3% of papillary carcinoma in Japan. In this study, we investigated the biological characteristics of 5 cases of macrofollicular variant. We reviewed the diagnosis and clinical course of 5 patients with macrofollicular variant. On preoperative ultrasonographic study, 2 cas...

Journal: :Cancer research 2011
Martin L Read Greg D Lewy Jim C W Fong Neil Sharma Robert I Seed Vicki E Smith Erica Gentilin Adrian Warfield Margaret C Eggo Jeffrey A Knauf Wendy E Leadbeater John C Watkinson Jayne A Franklyn Kristien Boelaert Christopher J McCabe

Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF expression to the thyroid gland (PBF-Tg mice) and found that these mice exhibited normal thyroid function, but a striking enlargement of the thyro...

2011
Martin L. Read Greg D. Lewy Jim C.W. Fong Neil Sharma Robert I. Seed Vicki E. Smith Erica Gentilin Adrian Warfield Margaret C. Eggo Jeffrey A. Knauf Wendy E. Leadbeater John C. Watkinson Jayne A. Franklyn Kristien Boelaert Christopher J. McCabe

Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized protooncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF expression to the thyroid gland (PBF-Tg mice) and found that these mice exhibited normal thyroid function, but a striking enlargement of the thyroi...

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