Myricetin (Myc) is one of the most important flavonoids in diet due to its abundance in foods with the highest antioxidant activity. The antioxidant activity of Myc was studied in cell-free and cell-based systems to evaluate the ROS protection efficiency of Myc. The studies were based on the assessment of reducing power of Myc according to ferric ion reduction and intracellular ROS level measur...

background: neuroblastoma is the most common extra cranial malignant solid tumor of childhood. various molecular and cytogenetic factors have been implicated in the pathogenesis of neuroblastoma, some of which have proven useful in predicting clinical behavior. over expression of the oncogen n-myc, is an important indicator of prognosis. materials and methods: our study was performed from 2004 ...

Background: Neuroblastoma is the most common extra cranial malignant solid tumor of childhood. Various molecular and cytogenetic factors have been implicated in the pathogenesis of neuroblastoma, some of which have proven useful in predicting clinical behavior. Over expression of the oncogen N-myc, is an important indicator of prognosis. Materials and Methods: Our study was performed from 20...

Background: Gastric cancer (GC) is considered as one of the most common types of cancer worldwide with poor prognosis and generally limited treatment options. Recent studies have indicated that HER2, MDM2, MYC, MET, and TP53 play an important role in the development of gastric cancer. Therefore, the aim of this study was to evaluate the incidence of amplification/deletion of these genes in pati...

background neuroblastoma is the most common extracranial malignant solid tumor in children under 5 years, and it is characterized by wide clinical and biological heterogeneity. n-myc oncogene amplification is considered to be one of the most important prognostic factors used to evaluate survival in these patients. objectives the aim of our study was to determine amplification of the n-myc oncog...

the aim of present study was to investigate the effect of individual and co-inoculation of trichoderma species and arbuscular mycorrhizal fungi (amf) on growth, mycorrhization, population of trichoderma, and wilt disease severity in pigeon pea (cajanus cajan l millsp). three species of trichoderma, namely, t. harzianum (th), t. virens (tr), and t. viride (tv) and consortium of amf (myc; mixture...

MXDs are transcription repressors that antagonize MYC-mediated gene activation. MYC, when associated with MIZ1, acts also as a repressor of subset genes, including p15 and p21. A role for in regulation MYC-repressed genes is not known. We report activate p21 U2OS cells. This activation required DNA binding by their interaction MIZ1. MXD mutants deficient MIZ1 interacted the MYC-binding partner ...

Background and Aims: Prostate cancer (PCa) is one of the most common cancers among men in Iran. Since changes in the regulation of proto-oncogenes expression are the main causes of most human cancers, including PCa, evaluating the expression of marker genes can be helpful for early diagnosis of cancer and better understanding of its etiology. The present study compared c-Myc expression level in...