in this paper, the researchers have investigated a concatenated robot move (crm) sequence problem and minimal part set (mps) schedule problem with different setup times for two-machine robotic cell. they have focused on simultaneous solving of crm sequence and mps schedule problems with different loading and unloading times. they have applied a simulated annealing (sa) algorithm to provide a go...

In this paper, the researchers have investigated a Concatenated Robot Move (CRM) sequence problem and Minimal Part Set (MPS) schedule problem with different setup times for two-machine robotic cell. They have focused on simultaneous solving of CRM sequence and MPS schedule problems with different loading and unloading times. They have applied a Simulated Annealing (SA) algorithm to provide a go...

This paper investigates the performance impact of lot-sizing rule (LSR) selection and freezing of the master production schedule (MPS) in multi-item single-level systems with a single resource constraint under deterministic demand. The results of the study show that the selection of LSRs and the parameters for freezing the MPS have a significant impact on total cost, schedule instability, and t...

This paper investigates the impact of freezing the master production schedule (MPS) in multi-item single-level systems with a single resource constraint under demand uncertainty. It also examines the impact of environmental factors on the selection of MPS freezing parameters. A computer model is built to simulate master production scheduling activities in a multi-item system under a rolling tim...

Revising the master production schedule (MPS) in a rolling planning horizon environment to improve plant performance is critical in process industries with sequence dependent changeovers. Plant performance is defined in terms of process changeover time, total shortages, and finished goods inventory. Two heuristics for revising the MPS are introduced and tested against a rolling horizon MPS that...

In this article, we propose a new way to improve master production schedule (MPS) stability under conditions of finite capacity. The purpose is to optimize product availability and customer service for typical situations encountered in the consumer goods industry. Using a comprehensive MPS model, we conduct a simulation study with experimental design to identify factors having a significant inf...

We study single machine scheduling problems with linear time-dependent deterioration effects and maintenance activities. Maintenance periods (MPs) are included into the schedule, so that the machine, that gets worse during the processing, can be restored to a better state. We deal with a job-independent version of the deterioration effects, i.e., all jobs share a common deterioration rate. Howe...

OBJECTIVES Our goal was to describe the neurobehavioral phenotype in mucopolysaccharidosis Type IIIB (MPS IIIB). Parents report that behavioral abnormalities are a major problem in MPS III posing serious challenges to parenting and quality-of-life for both patient and parent. Our previous research on MPS IIIA identified autistic symptoms, and a Klüver-Bucy-type syndrome as indicated by reduced ...

The introduction of long-circulating liposomes sterically stabilized by surface coating with polyethylene glycol has expanded the potential for drug targeting to tumors. In recent clinical studies, evidence of significant antitumor activity has been obtained with the industrially prepared formulation of long-circulating polyethylene glycol-coated liposomes containing doxorubicin, referred to as...

Interleaved Frequency Division Multiple Access (IFDMA) has the salient advantage of lower Peak-to-Average Power Ratio (PAPR) than its competitors like Orthogonal FDMA (OFDMA). A recent research effort ours put forth a new IFDMA transceiver design significantly less complex conventional transceivers. The reduces complexity by exploiting certain correspondence between signal processing and Cooley...