BACKGROUND The middle latency response (MLR) can be a powerful tool for assessing integrity of cortical and subcortical auditory structures. Most research on the MLR, however, is constrained to relatively slow repetition rates by the time window necessary for response acquisition. Maximum length sequence (MLS) paradigms enable the recording of the MLR at high repetition rates, which could reduc...

We investigate the analytical representation of potentials of mean force (pmf) using the Morse/long-range (MLR) potential approach. The MLR method had previously been used to represent potential energy surfaces, and we assess its validity for representing free-energies. The advantage of the approach is that the potential of mean force data only needs to be calculated in the short to medium rang...

The microcystin biodegradation potential of a natural bacterial community coexisting with a toxic cyanobacterial bloom was investigated in a water reservoir from central Spain. The biodegradation capacity was confirmed in all samples during the bloom and an increase of mlrA gene copies was found with increasing microcystin concentrations. Among the 24 microcystin degrading strains isolated from...

In certain statistical process control applications, quality of a process or product can be characterized by a function commonly referred to as profile. Some of the potential applications of profile monitoring are cases where quality characteristic of interest is modelled using binary,multinomial or ordinal variables. In this paper, profiles with multinomial response are studied. For this purpo...

Multipotent mesenchymal stromal cells (MSC) are receiving increased attention for their non-progenitor immunomodulatory potential. Cryopreservation is commonly used for long-term storage of MSC. Post-thaw MSC proliferation is associated with a lag-phase in vitro. How this lag-phase affect MSC immunomodulatory properties is unknown. We hypothesized that in vitro there is no difference in lymphoc...

CD83 is a marker of dendritic cell (DC) differentiation/activation and its expression in the mouse thymus contributes to CD4(+) T lymphocyte development. Its extrathymic role remains unclear despite the functional effects observed with CD83 fusion proteins or CD83 antibody and recent reports of potential ligands. We investigated the previously observed and presumed functional blockade of the al...

BACKGROUND To investigate influencing factors of the metastatic lymph nodes ratio (MLR) and whether it is related to survival in patients with gastric adenocarcinoma. METHODS We retrospectively evaluated the clinical features of 121 patients with gastric adenocarcinoma enrolled in our hospital between 2000 and 2007. The receiver operating characteristic (ROC) curve was used to determine the c...

BACKGROUND Diabetic retinopathy (DR) is a common complication of type 2 diabetes mellitus (T2DM) and the leading cause of blindness in adults. DR pathogenesis has not been fully elucidated, but inflammation is widely accepted to play an important role. Emerging evidence suggests that the platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and neutrophil-to-lymphocyte ratio (...

Wavelength selection is one of the key steps in quantitative spectral analysis, which reduces computation time while also improving prediction accuracy model. In this paper, we propose a wavelength algorithm based on ant colony optimization (ACO), absolute value regression coefficient multiple linear (MLR) model used as basis for evaluating importance wavelengths, and after full MLR modeling in...

The hamstring reflex response has been suggested to play a substantial role in knee joint stabilization during anterior tibial translation. The present study was performed to determine which afferent pathways contribute to the hamstring reflex as well as the potential effects of specific afferent pathways on functional knee stability. Short- and medium-latency hamstring reflexes (SLR and MLR) w...