background: radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. the scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (mird) method. at the end, the results of mird calculations were compared with thermoluminescent dosimeter (tld-100). ma...

UNLABELLED High-throughput deep-sequencing technology has generated an unprecedented number of expressed short sequence reads, presenting not only an opportunity but also a challenge for prediction of novel microRNAs. To verify the existence of candidate microRNAs, we have to show that these short sequences can be processed from candidate pre-microRNAs. However, it is laborious and time consumi...

*Corresponding author: Dr. Daryoush Shahbazi-Gahrouei, Dept. of Medical Physics and Medical Engineering, Isfahan University of Medical Sciences, Isfahan, Iran. Fax: +98 311 6688597 E-mail: [email protected] carcinoma after thyroidectomy (1-6). In this therapy method, the prescription of sodium iodine is done orally (7). Radioiodine is a beta emitting radionuclide with a physical half life ...

Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...

Background: Radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. The scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (MIRD) method. At the end, the results of MIRD calculations were compared with thermoluminescent dosimeter (TLD...

to improve the accuracy of the activity quantification and the image quality in scintigraphy, scatter correction is a vital procedure. the aim of this study is to compare the accuracy in calculation of absorbed dose to patients following bone scan with 99m tc-marked diphosphonates ( 99m tc-mdp) by two different methods of background correction in conjugate view method. this study involved 22 pa...

For the scope of risk assessment in protection against ionising radiation (occupational, environmental and medical) it is necessary to determine the radiation dose to specific body organs and tissues. For this purpose, a series of models of the human body were designed in the past, together with computer codes simulating the radiation transport and energy deposition in the body. Most of the com...

The internal dosimetry schema of the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine has provided a broad framework for assessment of the absorbed dose to whole organs, tissue subregions, voxelized tissue structures, and individual cellular compartments for use in both diagnostic and therapeutic nuclear medicine. The schema was originally published in 1968, r...

Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...