The main objective of this study was to analyze by real-time quantitative polymerase chain reaction (RT-qPCR) the expression patterns myosin heavy (MHC) isoforms (MHC-I, MHC-IIa, MHC-IIx) in sphenomandibularis portion temporalis muscle. We expected find differences between and other portions that could be related functional characteristics identified electromyography. dissected right muscle ten...

several studies have focused on polymorphisms of major histocompatibility complex (mhc) in sheep, ovar-mhc. this molecule plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. the best-characterized genetic control of disease resistance and immune response in animals is associated with mhc. numerous molecular genetic investigations have been und...

Abstract Theory predicts that parental heritable characteristics should shape sex allocation decisions when their effects on reproduction or survival are offspring sex-dependent. Numerous studies have questioned to what extent displayed by one of the parents matched theoretical expectations. This contrasts with handful investigated whether compatibility between could also trigger selective pres...

background: indigenous chickens could serve as precious genetic resources that should be considered in conservation and breeding programs. the major histocompatibility complex (mhc) has a strong association to disease resistance/susceptibility, production and reproduction traits in chicken. therefore, identifying its polymorphism in populations under selective breeding could be used for selecti...

Abstract Genes of the major histocompatibility complex (MHC) have long been linked to odor signaling and recently researchers’ attention has focused on MHC structuring microbial communities how this may in turn impact odor. However, understanding mechanisms through which could affect microbiota produce a chemical signal that is both reliable strong enough ensure unambiguous transmission behavio...

Major histocompatibility complex (MHC) class II deficiency is a primary immunodeficiency disease characterized by abnormality of MHC class II molecules surface expression on peripheral blood lymphocytes and monocytes. Clinical manifestations include extreme susceptibility to viral, bacterial, and fungal infections but the immunodeficiency is not as severe as SCID (severe combined immunodeficien...

Several studies have focused on polymorphisms of major histocompatibility complex (MHC) in sheep, Ovar-MHC. This molecule plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best-characterized genetic control of disease resistance and immune response in animals is associated with MHC. Numerous molecular genetic investigations have been und...

Abstract Mouse NK cells recognize MHC-I antigens via stochastically expressed inhibitory Ly49 receptors. The loss of expression on tumor (“missing self”) abrogates signals, resulting in activation. We have identified an anti-mouse pan mAb (M1/42), which blocks Ly49-MHC-I interactions but not TCR-MHC-I interactions. Administration M1/42 vivo markedly activated IFNg-producing that further drove t...