The aim of this study was to establish a freeze-drying process for melatonin-loaded lecithin/chitosan nanoparticles (NPs) to preserve their chemical and physical stability for a longer time period that what is possible in an aqueous suspension. Glucose and trehalose were investigated as potential excipients during freeze-drying of NP suspensions. Lecithin/chitosan NPs were characterised by mean...

AIMS To investigate the cause of turbidity in reconstituted lyophilised plasmas and to determine its effect on coagulometers. METHODS The turbidities of 20 normal plasmas and 16 reconstituted lyophilised plasmas were determined by comparing a 1 in 4 dilution in distilled water with a standard suspension in an Aminco Fluorocolorimeter (American Instrument Co) in nephelometric mode. The turbidi...

The aim of the study was to compare the effect of two low-cost, low technology traditional methods for drying starter cultures with standard lyophilisation. Lyophilised yeast cultures and yeast cultures preserved in dry rice cakes and dry plant fibre strands were examined for viable cell counts during 6 months storage at 4 and 25 °C. None of the yeast cultures showed a significant loss in viabl...

Silk foam-based terahertz waveguides are fabricated using lyophilisation and casting techniques. This work is motivated by the lack of biocompatible waveguides for low-loss guidance of THz for applications in remote sensing in biomedical and agro-alimentary industries.

Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs. MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions. Current technology of MSCs cryopreservation has significant disadvantages. Alternative technologies of mammalian cells preservation through lyophilisatio...

According to the reports of WHO, stability of Rev.1 vaccine should take more than one year, while the expiring date for the vaccine produced in Iran is 3 to 4 months, therefore any attempt to elongate the stability of this vaccine can solve many problems of the production including the request of Veterinary Organization of Iran in this regard. The objective of this study was to increase the sta...

Nawal Daraoui, Pascal Dufour, Hassan Hammouri. Benefits in using model based predictive control during drying and lyophilisation. 3rd European Drying Conference joint conference of the European Federation of Chemical Engineering (EFCE) Drying Working Party, Association Française de Séchage dans l’Industrie et l’Agriculture (AFSIA), May 2009, Lyon, France. 23 (1), pp.100-101, Cahier de l’AFSIA. ...

Recently, increasing attention has been paid to lecithin/chitosan nanoparticles as colloidal drug delivery system showing the great potential to improve the permeation of encapsulated drug across various biological barriers [1, 2]. However, the overall poor stability of colloidal nanoparticles in an aqueous medium is a significant drawback in their development perspective. Therefore, the aim of...

according to the reports of who, stability of rev.1 vaccine should take more than one year, while the expiring date for the vaccine produced in iran is 3 to 4 months, therefore any attempt to elongate the stability of this vaccine can solve many problems of the production including the request of veterinary organization of iran in this regard. the objective of this study was to increase the sta...