A novel G-protein-coupled receptor (GRL106) resembling neuropeptide Y and tachykinin receptors was cloned from the mollusc Lymnaea stagnalis. Application of a peptide extract from the Lymnaea brain to Xenopus oocytes expressing GRL106 activated a calcium-dependent chloride channel. Using this response as a bioassay, we purified the ligand for GRL106, Lymnaea cardioexcitatory peptide (LyCEP), an...

The present work aimed at studying the effect of Ambrosia maritima (Damsissa) on the viability of Lymnaea snails. Lymnaea snails used in these trials were acclimatized to laboratory conditions before use in the toxicity test. The snails were exposed to various concentrations (100-3000 mg/l) of dry powdered Damsissa, Ambrosia maritima was lethal to Lymnaea snails at concentration of 3000 mg/L af...

The pond snail Lymnaea stagnalis is among several mollusc species that have been well investigated due to the simplicity of their nervous systems and large identifiable neurons. Nonetheless, despite the continued attention given to the physiological characteristics of its nervous system, the genetic information of the Lymnaea central nervous system (CNS) has not yet been fully explored. The abs...

Neuropeptides are known to be important signaling molecules in several neural systems of the pond snail Lymnaea stagnalis. Although the functions of these peptides have been studied in many neurons, the nature of the postsynaptic signal transduction is mainly unknown. The cloning and characterization of neuropeptide receptors in Lymnaea thus would be very valuable in further elucidating peptide...

interacting neuronal networks make adaptive behavioral decisions. Further new avenues opened up by recent work on Lymnaea may lead to an understanding of how learning and homeostatic processes interact, to the building of sophisticated computer models of functional connectivity and interacting networks, and even to the development of applications to artificial complex systems. At a different le...

The 18S rDNA sequences of the six most common European Lymnaeidae species (Mollusca:Gastropoda:Basommatophora) have been obtained by direct PCR cycle sequencing and silver staining methods. The sequence alignment and secondary structures of the 18S rRNA gene of Lymnaea stagnalis, L. auricularia, L. peregra, L. palustris, L. glabra, and L. truncatula are analyzed. This gene proves to be a good m...

Forgetting may allow an animal to react more appropriately to current conditions, rather than continuing to exhibit a previously learned, possibly maladaptive behaviour based on previous experience. One theory is that forgetting is an active process, whereby the previously learnt response is replaced by new learning that interferes with the older memory. Hence, we hypothesized that an appropria...

Evolutionary Aspects of Neuropeptides and their Genes Structure and evolution of insulin and insulin-like growth factors in chordates p. 15 Relationships among the FMRFamide-like peptides p. 25 Molecular evolution of neurohypophysial hormone precursors p. 39 A vasopressin-related peptide in the mollusc Lymnaea stagnalis: Peptide structure, prohormone organization, evolutionary and functional as...

following the occurrence of two large outbreaks in gilan province, northern iran, the public health importance of human fascioliasis has increased significantly. the mixed infections of fasciola gigantica and f. hepatica within a given domestic animal individual suggest a very complicate picture of possible circulation ways of the parasite and the possibility for humans to be infected with both...