objective(s):sub-health has been described as a chronic condition of unexplained deteriorated physiological function, which falls between health and illness. in the present study, we evaluated the effects of lycium barbarum polysaccharide (lbp), a polysaccharide fraction purified from lycium barbarum (l. barbarum) on the sub-health mice. materials and methods:the sub-health model mice were buil...

The aim of the present study was to observe the effects of a general extract of Lycium bararum polysaccharides (LBPs) on methylmercury (MeHg)-induced damage in hippocampus neural stem cells (hNSCs). The hippocampal tissues of embryonic day 16 Sprague-Dawley rats were extracted for the isolation, purification and cloning of hNSCs. Following passage and proliferation for 10 days, the cells were a...

Lycium barbarum is a widely used Chinese herbal medicine prescription for protection of optic nerve. However, it remains unclear regarding the effects of Lycium barbarum polysaccharides, the main component of Lycium barbarum, on in vivo proliferation of adult ciliary body cells. In this study, adult rats were intragastrically administered low- and high-dose Lycium barbarum polysaccharides (1 an...

Lycium barbarum has been used in China for more than 2,000 years as a traditional medicinal herb and food supplement. Lycium barbarum contains abundant Lycium barbarum polysaccharides (LBPs), betaine, phenolics, carotenoids (zeaxanthin and β-carotene), cerebroside, 2-O-β-d-glucopyranosyl-l-ascorbic acid (AA-2βG), β-sitosterol, flavonoids and vitamins (in particular, riboflavin, thiamine, and as...

To determine the chlorogenic acid content in Lycium barbarum L. by HPLC (Reversed Phase Highperformance Liquid Chromatography); and to observe the protective effect of Lycium barbarum L. extract on Retinal Ganglion Cells (RGCs) in rats with ocular hypertension. A rat model of chronic ocular hypertension was established using healthy adult rats. The rats were randomized into the model group and ...

Lycium barbarum, a classic Chinese medicine, has a large variety of biological activities, including improvements in immunity, as well as anti-aging and anti-oxidation activities. It has been used to improve or restore deteriorating functions related to aging and diseases. Although its nerve protection effects also have been proved in vitro and in vivo, the molecular mechanism of action is not ...

We examine evolutionary relationships among the three genera in tribe Lycieae using DNA sequence data from the nuclear granule-bound starch synthase gene (GBSSI, waxy). Tribe Lycieae is comprised of the large cosmopolitan genus Lycium and the predominately South American genera Grabowskia and Phrodus. Phylogenetic results strongly suggest that Lycium contains Grabowskia and may also include Phr...

Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtained results demonstrated that the Lycium barbarum berries from Umbria region d...

The Lycium genus is widely used as a traditional Chinese medicine and functional food. Many of the chemical constituents of the genus Lycium were reported previously. In this review, in addition to the polysaccharides, we have enumerated 355 chemical constituents and nutrients, including 22 glycerogalactolipids, 29 phenylpropanoids, 10 coumarins, 13 lignans, 32 flavonoids, 37 amides, 72 alkaloi...