the introduction of ex vivo lung perfusion (evlp) in the practice of lung transplantation has allowed the reconditioning of the marginal grafts and their conversion into transplantable grafts. in addition, evlp can provide a platform for the application of various preventive measures to decrease the incidence of post-transplant complications. while the toronto team targets the attenuation of th...

inflammatory responses and innate immunologic reactions play an important role in the respiratory system. ex vivo lung perfusion (evlp) is considered a novel method in the evaluation and reconditioning of donor lungs prior to transplantation. however, evlp’s effect on inflammatory and metabolic markers of human lung tissue is unknown. this study investigated how the performance of evlp on brain...

conclusions increasing evidence supports the use of ecmo as a bridge to lt, reporting good outcomes. in the modern era of pah therapy, it is feasible to use prolonged ecmo support as a bridge to lung transplant, with the aim of weaning off this support; however, its use requires more experience and knowledge of long-term outcomes. introduction the use of extracorporeal membrane oxygenation (ecm...

conclusions in molecular epidemiology studies, nested pcr has higher sensitivity than pcr. results of this study support the colonization of p. jiroveci in patients receiving lung transplantation. patients who are carriers of p. jiroveci are at a higher risk of p. jiroveci pneumonia. results the genome of p. jiroveci was revealed by a 346 bp pcr product in the initial amplification and a 120 bp...

Cardiac valvular surgery in patients after lung transplantation is a challenging procedure, reports are scarce. We report 29-year-old patient who underwent concomitant mitral valve reconstruction and implantation of decellularized aortic homograft two years bilateral transplantation.

background: lung diseases are one of the major causes of morbidity and mortality after renal transplantation. the aim of the study is to define the risk factors for infectious and noninfectious pulmonary complications in kidney transplant patients. materials and methods:we prospectively studied 267 patients after renal transplantation. the kidney recipients were followed-up for the development ...

Lung transplantation is a therapeutic option for the treatment of advanced lung disease. The risk pulmonary infections increased in transplant recipients. We report case coinfection with Mycobacterium tuberculosis and Nocardia species recipient.

BACKGROUND Both single and bilateral lung transplantation are recognised options for patients who have end-stage chronic obstructive pulmonary disease (COPD); however, which procedure leads to longer survival remains unclear. We aimed to compare survival after each procedure by analysing data from the registry of the International Society for Heart and Lung Transplantation. METHODS We analyse...

BACKGROUND Lung transplantation and heart-lung transplantation represent surgical options for treatment of medically refractory idiopathic pulmonary arterial hypertension. The effect of the lung allocation score on wait-list and transplantation outcomes in patients with idiopathic pulmonary arterial hypertension is poorly described. METHODS AND RESULTS Adults diagnosed with idiopathic pulmona...

This Special Issue of Life features compelling original research and reviews related to current trends in lung transplantation (LTx) [...]