Split-hand/split-foot malformation is a rare limb malformation with median clefts of the hands and feet and aplasia/hypoplasia of the phalanges, metacarpals and metatarsals. When present as an isolated anomaly, it is usually inherited as an autosomal dominant form We report a case of autosomal dominant inheritance and discuss the antenatal diagnosis, genetic counseling and treatment for the mal...

Ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome (EEC) syndrome is a rare genetic disorder with an incidence of around 1 in 90,000 in population. It is known with various names including split hand-split foot-ectodermal dysplasia-cleft syndrome or split hand, cleft hand, or lobster claw hand/foot. We report first case of EEC with associated heart disease (Tetralogy of Fallot) w...

The association of ectrodactyly (lobster claw deformity or cleft of the hands and feet) and dacrocystitis was first reported by Cockayne in 19361, It was, however, Rudiger and others2 who stressed the association of atypical ectodermal dysplasia with ectrodactyly and cleft lip and palate and suggested the name EEC -syndrome, This is a rare congenital syndrome which shows both a familial autosom...

Fig. 1.Claw like deformity of both hands, right sided tibial hemimelia with hypoplastic three toed foot and a transverse cleft on planter side of left foot. Tibial hemimelia-split hand/foot syndrome (TH-SHFM) is a rare constellation of multiple congenital malformations which includes Ectrodactyly (Lobster claw deformity or Cleft hand/foot) with a wide range of phenotypes of absent tibia/tibial ...

Case Description- A 3-month-old, female mixed breed dog was presented to the Veterinary Teaching Hospital of Ferdowsi University with an obvious deformity in its right forelimb. Clinical Findings- - In clinical examination, there was a separation from elbow joint to the end of digits and a long skin cleft between these separated regions was seen. Radiographic examination revealed a wide space b...