Background: Medical use of ionizing radiation has direct/indirect undesirable effects on normal tissues. In this study, the radioprotective effect of arbutin in megavoltage therapeutic x-irradiated mice was investigated using serum alkaline phosphatase (ALP), alanine aminotransferase (ALT), and asparate amniotransferase (AST) activity measurements. Material and Methods: In this analytical...

Objective(s):Typhoid fever is a dreadful disease of a major threat to public health in developing countries. Vaccination with bacterial immunodominant components such as surface proteins may prove as a potent alternative to live attenuated vaccines. InvH, an important part of needle complex in type three secretion system (TTSS) plays important role in efficient bacterial adherence and entry int...

objective(s):typhoid fever is a dreadful disease of a major threat to public health in developing countries. vaccination with bacterial immunodominant components such as surface proteins may prove as a potent alternative to live attenuated vaccines. invh, an important part of needle complex in type three secretion system (ttss) plays important role in efficient bacterial adherence and entry int...

objective: dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. the present study was designed to investigate the ameliorative potential of different extracts of hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action.  materials and methods: male wistar rats were divided into 6...

Protein-depleted dogs are very susceptible to injurious agents-in particular, chloroform. Methionine given shortly before chloroform anesthesia will give complete protection against chloroform. Methionine (or cysteine plus choline) given 3 or 4 hours after chloroform anesthesia will give significant protection against the liver injury of chloroform anesthesia. Methionine given more than 4 hours...

The present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of Wrightia tinctoria (containing lupeol, b -amyrin and b -sitosterol) on CCl 4 -induced hepatotoxicity in the rat. CCl 4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatt...

Since the demonstration of sterile protection afforded by injection of irradiated sporozoites, CD8+ T cells have been shown to play a significant role in protection from liver-stage malaria. This is, however, dependent on the presence of an extremely high number of circulating effector cells, thought to be necessary to scan, locate, and kill infected hepatocytes in the short time that parasites...

the present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of wrightia tinctoria (containing lupeol, b -amyrin and b -sitosterol) on ccl 4 -induced hepatotoxicity in the rat. ccl 4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatty degeneratio...

AIM Despite intensive research, liver diseases represent a significant health problem and current medicine does not offer a substance able to significantly inhibit the hepatotoxicity leading to various stages of liver disease. Based on our previously published studies showing the protective effects of a glucan-humic acid (HA) combination, we focused on the hypothesis that the combination of the...