background: occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. this study was designed to investigate the clinical manifestations and pathological parameters of h...

conclusions any discrepancy between histopathologic changes in time-zero biopsies and pattern of early liver laboratory alterations may be considered as a warning for causes other than pri. objectives the aim of this study was to show the correlation between histopathologic changes of pri and the alterations in liver tests in the early post-transplantation period. materials and methods between ...

background cannabis is one of the most widely used illicit drugs in india and worldwide. it is considered to have a minimal effect on physical health. objectives the aim of this study was to compare the laboratory profiles of treatment-seeking patients who were cannabis dependent, and drug users who concurrently use other substances, with non-users. materials and methods medical records of pati...

conclusions aed improved liver enzymes in obese women. however, mild, transient increases in alt and ast values can be observed immediately after an nfd in women. results of 108 participants, 50 women in aed group and 50 women in nfd group completed the protocol of the study (response rate: 92.6 %). the aed led to a median weight loss of 3.79 kg (interquartile range: 4.4 kg). significant decrea...

background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...

conclusions the prevalence of abnormal lfts in iranian morbid obese patients is in high status especially the level of alkp. liver ultrasonography has high sensitivity for the fatty liver in morbid obese patients but lfts rise only in few patients with fatty liver. background obesity, a major risk factor for fatty liver disease, is increasing worldwide. morbid obese patients have a higher preva...

the liver is a multifactorial organ which is involved in a number of critical excretory, synthetic and metabolic functions. although the term 'liver function test' is commonly used, it is imprecise since many of the tests, such as transaminase, do not measure liver function. therefore, these tests should be referred to as 'liver enzyme tests', and 'liver function tests' should be the term used ...