liquid paraffin has been suggested as a good laxative comparing to lactulose as a treatment option in pediatric constipation. this study was performed to compare liquid paraffin with lactulose in pediatric constipation. a total of 247 patients (127 males and 120 females) aged 2-12 years (mean 4.1 ± 2.7 years) with chronic functional constipation were included in an 8 week, randomized, controlle...

By scanning biological tissues in vivo and in vitro with optical coherence tomography, it is found that liquid paraffin can enhance the percutaneous penetration of glycerol in deep layers of tissue and take synergistically optical clearing effect with glycerol. It is shown from experimental results that 30% - 50% liquid paraffin glycerol solutions have the best enhancement effect. Considering t...

BACKGROUND AND THE PURPOSE OF THE STUDY Functional constipation is prevalent in children. Recently polyethylene glycol has been introduced as an effective and safe drug to treat chronic constipation. There are only a few clinical trials on comparison of PEG and liquid paraffin in childhood constipation. The purpose of this study was to evaluate clinical efficacy and safety of PEG 3350 solution ...

We evaluated cells and lipids recovered in the bronchoalveolar lavage fluid from seven patients with liquid paraffin pneumonitis. For each patient, the BALF was whitish with oil droplets on the surface. Alveolar macrophages contained numerous, large vacuoles that did not react with May-Grunwald-Giemsa, Papanicolaou, or periodic acid-Schiff but were stained in black with Sudan B, orange with Sud...

The paper demonstrates the feasibility of the gel-clot method for the analysis of bacterial endotoxins in water extracts of ultrapure paraffin oil which is a water insoluble oily medical device. Because ultrapure paraffin oil is water insoluble oily liquid, the ultrapure paraffin oil (10 mL) was shaken with 10 mL water for 15 minutes at 2000 rpm, the endotoxin present was extracted to the aqueo...

The first description of oil aspiration pneumonia in man was by Laughlen in 1925. He described 4 cases diagnosed at necropsy: 3 of the patients were infants and 1 was an adult. In 2 cases the administration of liquid paraffin by mouth was incriminated and in the other 2 oily nasal drops had been used. Pinkerton (1927) described 6 cases diagnosed at necropsy, 5 were infants and 1 was a 6-year-ol...