background: mature t/ nk-cell neoplasms are a rare group of disorders and their presentation as leukemia is even rarer. most of the previous studies have focused on mature b-cell lineage leukemias and there is a paucity of data on mature t/nk-cell lineage leukemias. we, therefore, planned this study to analyze their spectrum, frequency, morphology and immunophenotypic features. methods: all cas...

undoubtedly, the legislator has paid special attention toward protection of lineage of persons so as the weakest evidence like lottery may be used to establish a lineage under the shiite jurisprudence. therefore, the value and credit of scientific evidence such as dna test in proving lineage is very clearly acceptable. but the point worth considering here is evaluating whether such scientific e...

Background: Aberrant expression of cross-lineage antigens gives valuable insight into the diagnosis and prognosis of acute leukemia. In countries like India, cytogenetic tests are widely accessible. Exploring the prognostic value of an accessible test is of great importance. Therefore, establishing a population-specific immunophenotype database will enable to design an antibody panel equipped t...

acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. the conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. it has been rarely reported in the literature. in leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. herein, we rep...

Acute leukemia which is the most common cancer in children is a heterogeneous group of clonal malignancies. The conversion of the leukemic cell lineage during the course of the disease or later is termed lineage switch. It has been rarely reported in the literature. In leukemia lineage switch, conversions from lymphoblastic leukemia to myeloid leukemia or vice versa are reported. Herein, we rep...

background and aims: the e2f family of transcription factors is encoded by at least eight genes, e2f1-8. these proteins are important targets of the retinoblastoma protein (rb) contributed in regulation of transcription, cell cycle and apoptosis. the aim of this study was to investigate the expression levels of e2f protein family including e2f1, e2f2, e2f7, e2f8 and rb1 in the lineage negative ...

Historical biogeography can be divided into two subdisciplines: taxon biogeography and area biogeography. In the former we are interested in reconstructing the geographic distribution history of a particular group of organisms. Questions we may be interested in answering include: Where did the organisms originate? How did they colonize the areas in which they live today? When did they first com...

The Yule (pure-birth)model is the simplest nullmodel of speciation; each lineage gives rise to a new lineage independentlywith the same rateλ.We investigate the expected length of an edge chosen at random from the resulting evolutionary tree. In particular, we compare the expected length of a randomly selected edge with the expected length of a randomly selected pendant edge.We provide some exa...