background:   primary bone lymphoma or non-hodgkin lymphoma of bone is a rare disease. there are only a few case series of stage ie of this condition in medical literature. the aim of this study is to determine the rate of survival   for stage ie after combined modality treatment, the rate of local recurrence, and the results of limb salvage in cases   of local recurrence.     methods:   we col...

background: massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. the purpose of this study was to analyze the outcome of these procedures at imam reza hospital, mashhad university of medical sciences. methods: in this study, 113 cases have been presented. eleven cases were excluded (patients has a traumatic...

PURPOSE Leg threatening injuries present patients and clinicians with a difficult decision: whether to pursue primary amputation or limb salvage? The purpose of our study was to review the literature in an effort to inform this management decision. METHODS We systematically searched and selected observational studies that reported on individuals presenting with leg threatening injuries compar...

Osteosarcoma is the most common primary malignant bone tumor; its standard treatment includes neoadjuvant chemotherapy combined with surgery. Neoadjuvant chemotherapy has significantly improved the 5-year survival and limb salvage rates in osteosarcoma since the 1870s. The survival rate of patients with limb salvage was not inferior to that of amputees, and therefore, limb salvage has become th...

BACKGROUND The presence of a pathological fracture due to osteosarcoma (OS) has been considered a high risk factor for dissemination and an indication for immediate amputation. With current neoadjuvant chemotherapy regimens there is a trend towards limb salvage procedures in selected cases. The aim of this study is to assess the outcome of patients treated with amputation versus patients treate...

BACKGROUND The goal of salvage surgery in the diabetic foot is maximal preservation of the limb, but it is also important to resect unviable tissue sufficiently to avoid reamputation. This study aims to provide information on determining the optimal amputation level that allows preservation of as much limb length as possible without the risk of further reamputation by analyzing several predicti...

Background & Aims: Osteosarcoma is one of the most prevalent malignant bone tumors . This study is designed to assess the prognostic effect of pathologic fracture and treatment options on survival of patients with osteosarcoma. Materials & Methods: In this study, prognosis of 106 patients with limb osteosarcoma, which were treated at three  hospitals in Tehran from April to August 2012 ...