results brdu ihc showed a significant decrease in neurogenesis following tld in both sexes showing more severity in male rats than in female rats. results of nissl staining and mwm also confirmed the brdu findings. regarding sexual dimorphism, our data showed no significant sex differences in the dg area of the hippocampus. conclusions sex-dependent reduction in neurogenesis following tld could...

objective(s): there are few reports have demonstrated the effect of a change-in-light experience on the structure and function of hippocampus. a change-in-light experience also affects the circadian pattern of melatonin secretion. this study aimed to investigate developmental effect of exogenous melatonin on synaptic plasticity of hippocampus of light deprived rats. materials and methods: the e...

Dark is a generally known potent stimulus for melatonin secretion. Studies have also reported that pineal and hypophyseal endocrine secretions are influenced by nutritional factors. The study was designed to investigate the combined effect of selenium supplementations and light deprivation on pineal and hypophyseal secretions in female Wistar rats. 36 female cyclical Wistar rats were divided in...

A number of previous studies have indicated that an environmental manipulation, 48 h of light deprivation (LD), produces virtually complete and permanent behavioral recovery of function from neglect induced by medial agranular cortex (AGm) lesions. LD-induced behavioral recovery from neglect is correlated with physiological changes in the dorsolateral striatum, an area that contains the project...

Long-term deprivation of visual input for several days or weeks leads to marked changes in the excitability and function of the occipital cortex. The time course of these changes is poorly understood. In this study, we addressed the question whether a short period of light deprivation (minutes to a few hours) can elicit such changes in humans. Noninvasive transcranial magnetic stimulation (TMS)...

Background & Aims: Change in visual experience impairs circadian rhythms. In this study, The effects of visual deprivation during critical period of brain development and melatonin intake on synaptic plasticity of hippocampal CA1 neurons were evaluated. Methods: This experimental study was done on male rats kept in standard 12 hour light/dark condition (L...

OBJECTIVE The aim of this study is to analyze the effect of light deprivation on the expression of vascular endothelial growth factor (VEGF) and neovascularization in the retina of neonatal rats. MATERIALS AND METHODS Thirty-six neonatal SD rats (male and female) were used in this study. These rats were numbered randomly and assigned into 3 groups (12 rats in each group), ie. 10-day group (ro...

Background:  Maternal sleep deprivation is known to reduce neurogenesis in the hippocampus during pregnancy. Also, it damages and impairs cognitive functions such as learning and memory in the neonates.  Objectives: Rosmarinus officinalis (rosemary) extract can play an important role in the treatment of cognitive impairments by inhibiting oxidative stress. This study aimed to investigate the r...

purpose the aim of this study was to determine the effect of one night's sleep deprivation on anaerobic performance and reaction time of subjects in the morning of the following day. methods eighteen male college student athletes were studied twice in a balanced, randomized design. subjects were measured for peak power, mean power and reaction time. results the performance showed no significant...

During a critical period of postnatal age sensory experience has a profound effect on maturation of visual cortical wiring. Electrophysiological evidence is indicating a substantial effect of visual deprivation on the visual cortical response properties. In this study we evaluated effect of light deprivation during a limited time of postnatal age on two aspects of spatial (working and reference...