نتایج جستجو برای: Lifespan

تعداد نتایج: 15331  

Journal: :iranian journal of veterinary research 2012
a. niasari-naslaji m. eslami y. nazem

this study investigated the effect of gnrh analogues on inducing ovulation of dominant follicle (df)and subsequent corpus luteum (cl) lifespan in the presence of norgestomet implant in holstein heifers. onday 6 to 8 of the estrous cycle (day 0 of the experiment), all heifers (n=15) received norgestomet implantfollowed by prostaglandin injection on days 0 and 1. on day 4, group 1 (n=4) and 2 (n=...

Journal: :jundishapur journal of microbiology 0
bedia palabiyik department of molecular biology and genetics, faculty of science, istanbul university, istanbul, turkey; department of molecular biology and genetics, faculty of science, istanbul university, istanbul, turkey. tel: +90-2124555700 farinaz jafari ghods department of molecular biology and genetics, faculty of science, istanbul university, istanbul, turkey

conclusions our results demonstrated no significant correlation between the ird5 lifespan and the trehalose concentration. likewise, the correlation between lifespan extension, trehalose accumulation, and cellular resistance to hydrogen peroxide was not significant. results the lifespan of the ird5 mutant was significantly longer that of either the ird11 mutant or the wild type cells. under rep...

Sarac , H, Sari, M,

Presently, the use of protective food additives such as benzoic acid and sodium nitrate is quite common. However, it was found that these additives, which initially appeared to be harmless, led to the emergence of a number of health problems. Cancer and diseases and deaths with no apparent causes are among the leading concerns. Therefore, the studies which can reveal the genotoxic potential of ...

Journal: :Proceedings of the National Academy of Sciences 2013

2014
David E Harrison Randy Strong David B Allison Bruce N Ames Clinton M Astle Hani Atamna Elizabeth Fernandez Kevin Flurkey Martin A Javors Nancy L Nadon James F Nelson Scott Pletcher James W Simpkins Daniel Smith J Erby Wilkinson Richard A Miller

Four agents--acarbose (ACA), 17-α-estradiol (EST), nordihydroguaiaretic acid (NDGA), and methylene blue (MB)--were evaluated for lifespan effects in genetically heterogeneous mice tested at three sites. Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). This sexual dimorphism in ACA lifespan effect could not be explained by d...

A. Niasari-Naslaji, M. Eslami Y. Nazem

This study investigated the effect of GnRH analogues on inducing ovulation of dominant follicle (DF)and subsequent corpus luteum (CL) lifespan in the presence of norgestomet implant in Holstein heifers. Onday 6 to 8 of the estrous cycle (day 0 of the experiment), all heifers (n=15) received norgestomet implantfollowed by prostaglandin injection on days 0 and 1. On day 4, group 1 (n=4) and 2 (n=...

Journal: :PLoS Genetics 2008
James J. Collins Kimberley Evason Christopher L. Pickett Daniel L. Schneider Kerry Kornfeld

Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide in lifespan extension is unknown, and elucidating how ethosuximide functions is important for defining endogenous processes that influence lif...

2016
Arnaud Tauffenberger Alexandra Vaccaro J. Alex Parker

Mitochondrial function is central to longevity and an imbalance in mitonuclear protein homeostasis activates a protective response called the mitochondrial unfolded protein response (UPRmt). Toxic compounds damaging mitochondria trigger the UPRmt, but at sublethal doses these insults extend lifespan in simple animals like C. elegans. Mitochondria are the main energy suppliers in eukaryotes, but...

Journal: :The New phytologist 2012
M Luke McCormack Thomas S Adams Erica A H Smithwick David M Eissenstat

Although linkages of leaf and whole-plant traits to leaf lifespan have been rigorously investigated, there is a limited understanding of similar linkages of whole-plant and fine root traits to root lifespan. In comparisons across species, do suites of traits found in leaves also exist for roots, and can these traits be used to predict root lifespan? We observed the fine root lifespan of 12 temp...

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