Lawsone is a pigment that occurs naturally in plants. It has been used as a skin and hair dye for a long time. Moreover, its different biological activities have been reported. The present study focused on the effect of lawsone on a plant cell model represented by tobacco BY-2 cell suspension culture, which is used as a model comparable with the HeLa cells. It has been shown that lawsone inhibi...

Wound healing potential of different extracts of henna leaves i.e. Lawsonia inermis Linn. was evaluated on the rat excision and incision wound models. Lawsone isolated from the leaves was also screened for same pharmacological activity.It was observed that the oral administration as well as topical application of ethanol extract of henna leaves and lawsone exhibited significanthealing response ...

The efficacy of lawsone against L-arginine induced acute pancreatitis was determined at 24 h by determination of serum levels of amylase, lipase and proinflammatory cytokines [tumor necrosis factor (TNF)-alpha, C-reactive proteins and interleukin (IL)], pancreatic myeloperoxidase (MPO) activity, lipid peroxidation (thiobarbituric acid reactive substances (TBARS)], nitrate/nitrite levels, and th...

The C-3 substituted phenylazo derivatives of lawsone (2-hydroxy-l,4 p-naphthoquinone, III) were synthesized and characterized. The X-ray crystal structure was determined for the ligand 3-(3'-methyl phenylazo) lawsone. The copper complexes of these derivatives were found to possess 1:2 metal stoichiometry and square planar geometries with intermolecular stackings, resulting in antiferromagnetic ...

The synthesis of a new class lawsone enaminone derivatives by using lawsone, triethyl orthoformate and aromatic amines in the presence guanidinium chloride under solvent-free conditions has been developed.

OBJECTIVE To evaluate the in vitro oxidation potential of lawsone (2-hydroxy-1,4 naphthoquinone). Lawsone is a chemical present in henna, the crushed leaves of which are used worldwide as a cosmetic agent to stain the hair, skin, and nails. METHODOLOGY Venous blood from glucose-6-phosphate dehydrogenase (G6PD)-normal and G6PD A- subjects were incubated with various amounts of lawsone for 2 ho...

The present study elucidates the preliminary phytochemical analysis and High Performance Thin Layer Chromatography (HPTLC) fingerprint analysis of lawsone extract of the leaves of Lawsonia inermis (henna) and evaluates their regions and products based quantitative estimations. The lawsone content has been evaluated quantitatively in two plants samples collected from Rewa and Bhopal and one comm...

lawsone a natural pigment present in the henna leaves has been used as a skin and hair dye since 1400 bc. the concentration of this natural compound in leaves varies from place to place depending upon many of the environmental factors and the highest quantity reported so far is about 1% of the dry mass. heretofore, it has been reported that natural colored extracts and isolate from henna leaves...

The naphthoquinones lapachol and dichloroallyl lawsone readily undergo oxidative ring fission when incubated with several fungi and streptomycetes. Penicillium notatum was employed to produce the ring fission product of dichloroallyl lawsone which was isolated and characterized by spectral analyses and chemical synthesis. The mechanism of oxidative ring fission of lapachol was studied by growin...

Saprolegniasis is one of the most devastating oomycete diseases in freshwater fish which is caused by species in the genus Saprolegnia including Saprolegnia parasitica. In this study, we isolated the strain of S. parasitica from diseased rainbow trout in Korea. Morphological and molecular based identification confirmed that isolated oomycete belongs to the member of S. parasitica, supported by ...